Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …

Extracellular vesicles (EVs) are small lipid bilayer-delimited particles that are naturally
released from cells into body fluids, and therefore can travel and convey regulatory functions …

Simple Summary In this study, we explore for the first time an innovative tool for organ
preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from …

Chronic kidney disease (CKD) is rising in global prevalence and has become a worldwide
public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and …

Regenerative medicine (RM) is changing how we think and practice transplant medicine. In
regenerative medicine, the aim is to develop and employ methods to regenerate, restore or …

Kidney transplantation is the optimal treatment for patients with end-stage renal disease
however, early detection and timely treatment of graft injury remain a challenge. Precise and …

Organ transplantation is essential and crucial for saving and enhancing the lives of
individuals suffering from end-stage organ failure. Major challenges in the medical field …

The use of extended criteria donor grafts is a promising strategy to increase the number of
organ transplantations and reduce waitlist mortality. However, these organs are often …

Acute kidney injury (AKI) is a sudden decline of renal function and represents a global
clinical problem due to an elevated morbidity and mortality. Despite many efforts, currently …

NADH: ubiquinone oxidoreductase core subunit S8 (NDUFS8) is an essential core subunit
and component of the iron-sulfur (FeS) fragment of mitochondrial complex I directly involved …