Type 2 Diabetes is a major public health threat, and its prevalence is increasing worldwide.
The abnormal accumulation of islet amyloid polypeptide (IAPP) in pancreatic β-cells is …

Abstract Alzheimer's disease (AD), the most prevalent neurodegenerative disease, is
characterized by extracellular accumulation of amyloid-beta protein (Aβ), which is believed …

The self-assembly of aromatic amino acids has been widely studied due to their ability to
form well-defined amyloid-like fibrillar structures. Herein, for the first time, we report the …

Self-assembly is a process of spontaneous organization of molecules as a result of non-
covalent interactions. Organized self-assembly at the nano level is emerging as a powerful …

Islet amyloid polypeptide (IAPP) is a 37-residue polypeptide hormone secreted by the
pancreatic β-cells. IAPP plays a role in glycemic regulation, but in the pre-type-2 diabetic …

The islet amyloid polypeptide (IAPP) is a 37-residue aggregation-prone peptide hormone
whose deposition as insoluble fibrils in the islets of Langerhans is associated with type II …

The microtubule-associated protein tau is involved in more than 20 different neurological
disorders characterized by aberrant intracellular aggregation of tau in the brain. Here, we …

Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It
rapidly forms an amyloid, which is considered physiologically important for efficient packing …

The short peptide fragment NFGAIL (IAPf) is a well-known amyloidogenic peptide (22–27),
derived from human islet amyloid polypeptide (hIAPP), whose fibrillar structure is often used …

Experimental studies of amyloids encounter many challenges. There are many methods
available for studying proteins, which can be applied to amyloids: from basic staining …