The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

The surfaces of human internal organs are lined by a mucus layer that ensures symbiotic
relationships with commensal microbiome while protecting against potentially injurious …

In the lungs, defective CFTR associated with cystic fibrosis (CF) represents the nidus for
abnormal mucus clearance in the airways and consequently a progressive lung disease …

Cystic fibrosis is a common genetically inherited, multisystem disorder caused by loss of
function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, an …

Toward an optimized strategy of using various airway mucus clearance techniques to treat
critically ill COVID-19 patients Page 1 Toward an optimized strategy of using various airway …

Individuals with cystic fibrosis (CF) suffer from severe respiratory disease due to a genetic
defect in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which …

Why is a healthy person protected from Pseudomonas aeruginosa infections, while
individuals with cystic fibrosis or damaged epithelium are particularly susceptible to this …

Pseudomonas aeruginosa is an opportunistic bacterial pathogen commonly associated with
cystic fibrosis (CF) lung infection. Numerous studies have investigated the mechanism of …