Background Chronic restraint stress (CRS) is widely used to recapitulate depression
phenotypes in rodents but is frequently criticized for a perceived lack of efficacy. The aim of …

Electroconvulsive therapy (ECT) is a well-established treatment for adults with mood
disorders. However, its use in child and adolescent populations is less common. At the same …

Adolescent mental health (MH) disorders with striking prominence include anxiety, self-harm
and depression. The current review aims to highlight high-quality reviews of novel …

Importance Little evidence exists on neurological adverse events (movement disorders and
seizures) that occur during adjuvant use of antipsychotics with antidepressants, especially in …

Background Most adults fail to achieve remission from common mental health conditions
based on pharmacological treatment in primary care alone. There is no data synthesising …

Akin to a William Morris tapestry, Dr Stephen Rosenman explicates the ACE (activity,
cognition and emotion) Model described in the recent mood disorder clinical practice …

This thesis utilises advanced statistical techniques to examine the relationship between
combined modifiable lifestyle behaviours and well-being in children and adolescents. The …