Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact

Q Fan, C Eichner, M Afzali, L Mueller, CMW Tax… - Neuroimage, 2022 - Elsevier
Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

[HTML][HTML] Surface-based tracking for short association fibre tractography

D Shastin, S Genc, GD Parker, K Koller, CMW Tax… - Neuroimage, 2022 - Elsevier
It is estimated that in the human brain, short association fibres (SAF) represent more than
half of the total white matter volume and their involvement has been implicated in a range of …

Fixel based analysis of white matter alterations in early stage cerebral small vessel disease

M Petersen, BM Frey, C Mayer, S Kühn, J Gallinat… - Scientific reports, 2022 - nature.com
Cerebral small vessel disease (CSVD) is a common cause of morbidity and cognitive
decline in the elderly population. However, characterizing the disease pathophysiology and …

[HTML][HTML] A large-scale investigation of white matter microstructural associations with reading ability

SL Meisler, JDE Gabrieli - NeuroImage, 2022 - Elsevier
Reading involves the functioning of a widely distributed brain network, and white matter
tracts are responsible for transmitting information between constituent network nodes …

[HTML][HTML] Timing of selective basal ganglia white matter loss in premanifest Huntington's disease

P Zeun, P McColgan, T Dhollander, S Gregory… - NeuroImage: Clinical, 2022 - Elsevier
Objectives To investigate the timeframe prior to symptom onset when cortico-basal ganglia
white matter (white matter) loss begins in premanifest Huntington's disease (preHD), and …

Sensitivity of diffusion MRI to white matter pathology: influence of diffusion protocol, magnetic field strength, and processing pipeline in systemic lupus erythematosus

EN Kornaropoulos, S Winzeck, T Rumetshofer… - Frontiers in …, 2022 - frontiersin.org
There are many ways to acquire and process diffusion MRI (dMRI) data for group studies,
but it is unknown which maximizes the sensitivity to white matter (WM) pathology. Inspired by …

[HTML][HTML] Retinal ganglion cell endowment is correlated with optic tract fiber cross section, not density

HO Taskin, Y Qiao, VJ Sydnor, M Cieslak, EB Haggerty… - Neuroimage, 2022 - Elsevier
There is substantial variation between healthy individuals in the number of retinal ganglion
cells (RGC) in the eye, with commensurate variation in the number of axons in the optic …

[HTML][HTML] Longitudinal changes of ADHD symptoms in association with white matter microstructure: A tract-specific fixel-based analysis

CG Damatac, S Soheili-Nezhad, GB Freches… - NeuroImage: Clinical, 2022 - Elsevier
Background Variation in the longitudinal course of childhood attention deficit/hyperactivity
disorder (ADHD) coincides with neurodevelopmental maturation of brain structure and …

Mutation‐related magnetization‐transfer, not axon density, drives white matter differences in premanifest Huntington disease: Evidence from in vivo ultra‐strong …

C Casella, M Chamberland, PL Laguna… - Human Brain …, 2022 - Wiley Online Library
White matter (WM) alterations have been observed in Huntington disease (HD) but their role
in the disease‐pathophysiology remains unknown. We assessed WM changes in …

Neonatal encephalopathy prediction of poor outcome with diffusion-weighted imaging connectome and fixel-based analysis

JW Jeong, MH Lee, N Fernandes, S Deol, S Mody… - Pediatric …, 2022 - nature.com
Background Better biomarkers of eventual outcome are needed for neonatal
encephalopathy. To identify the most potent neonatal imaging marker associated with 2-year …