[HTML][HTML] Properties and functions of fibroblasts and myofibroblasts in myocardial infarction

H Venugopal, A Hanna, C Humeres, NG Frangogiannis - Cells, 2022 - mdpi.com
The adult mammalian heart contains abundant interstitial and perivascular fibroblasts that
expand following injury and play a reparative role but also contribute to maladaptive fibrotic …

Macrophages in myocardial infarction

A Kubota, NG Frangogiannis - American Journal of …, 2022 - journals.physiology.org
The heart contains a population of resident macrophages that markedly expands following
injury through recruitment of monocytes and through proliferation of macrophages. In …

[HTML][HTML] Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure

C Humeres, AV Shinde, A Hanna… - The Journal of …, 2022 - Am Soc Clin Investig
Repair of the infarcted heart requires TGF-β/Smad3 signaling in cardiac myofibroblasts.
However, TGF-β–driven myofibroblast activation needs to be tightly regulated in order to …

[HTML][HTML] Identification of macrophages in normal and injured mouse tissues using reporter lines and antibodies

B Chen, R Li, A Kubota, L Alex, NG Frangogiannis - Scientific reports, 2022 - nature.com
Reliable tools for macrophage identification in mouse tissues are critical for studies
investigating inflammatory and reparative responses. Transgenic reporter mice and anti …

[HTML][HTML] Plasma exosome miRNAs profile in patients With ST-segment elevation myocardial infarction

R Guan, K Zeng, B Zhang, M Gao, J Li… - Frontiers in …, 2022 - frontiersin.org
Background Circulating microRNAs (miRNAs) have been found to have different
expressions in different phases of acute myocardial infarction. The profiles of plasma …