Extending applications of AFM to fluidic AFM in single living cell studies

Y Qiu, CC Chien, B Maroulis, J Bei… - Journal of cellular …, 2022 - Wiley Online Library
In this article, a review of a series of applications of atomic force microscopy (AFM) and
fluidic Atomic Force Microscopy (fluidic AFM, hereafter fluidFM) in single‐cell studies is …

High-resolution mass measurements of single budding yeast reveal linear growth segments

AP Cuny, K Tanuj Sapra, D Martinez-Martin… - Nature …, 2022 - nature.com
The regulation of cell growth has fundamental physiological, biotechnological and medical
implications. However, methods that can continuously monitor individual cells at sufficient …

Volume growth in animal cells is cell cycle dependent and shows additive fluctuations

C Cadart, L Venkova, M Piel, MC Lagomarsino - Elife, 2022 - elifesciences.org
The way proliferating animal cells coordinate the growth of their mass, volume, and other
relevant size parameters is a long-standing question in biology. Studies focusing on cell …

Physical cytometry: detecting mass-related properties of single cells

Y Zhao, L Gu, H Sun, X Sha, WJ Li - ACS sensors, 2022 - ACS Publications
The physical properties of a single cell, such as mass, volume, and density, are important
indications of the cell's metabolic characteristics and homeostasis. Precise measurement of …

Biomass measurements of single neurites in vitro using optical wavefront microscopy

L Durdevic, A Relaño Ginés, A Roueff… - Biomedical optics …, 2022 - opg.optica.org
Quantitative phase microscopies (QPMs) enable label-free, non-invasive observation of
living cells in culture, for arbitrarily long periods of time. One of the main benefits of QPMs …

AFM microfluidic cantilevers as weight sensors for live single cell mass measurements

CC Chien, J Jiang, B Gong, T Li… - … Science and Technology, 2022 - iopscience.iop.org
Reliably measuring small mass changes at the single-cell level is challenging. In this
manuscript, we report the use of microfluidic cantilevers in liquid with sub-nanogram scale …

Tissue confinement regulates cell growth and size in epithelia

J Devany, MJ Falk, LJ Holt, A Murugan, ML Gardel - BioRxiv, 2022 - biorxiv.org
Cell proliferation is a central process in tissue development, homeostasis and disease. Yet
how proliferation is regulated in the tissue context remains poorly understood. Here, we …

基底硬度与形貌协同对大鼠骨髓间充质干细胞成骨分化的影响

刘洋, 韩东, 华闻达, 何飞 - 医用生物力学, 2022 - pubs.cstam.org.cn
目的探讨基底硬度与形貌协同对大鼠骨髓间充质干细胞(rat bone mesenchymal stem cells,
rBMSCs) 形态, 增殖以及成骨分化的影响. 方法分别在硬度为3.5 MPa, 槽, 脊宽为0.3 μm …

[PDF][PDF] Computational Investigation of Cell Migration Behavior in a Confluent Epithelial Monolayer.

J Bai, X Zeng - CMES-Computer Modeling in Engineering & …, 2022 - cdn.techscience.cn
Cell migration plays a significant role in many biological activities, yet the physical
mechanisms of cell migration are still not well understood. In this study, a continuum physics …

[HTML][HTML] Measuring the size and growth of single cells

A Gong, M Min - Biophysics Reports, 2022 - ncbi.nlm.nih.gov
The size and growth of a cell can be described by three related physical parameters:
volume, density and mass. All the three are coupled to numerous biochemical reactions and …