Non-alcoholic fatty liver disease (NAFLD) represents a predominant hepatopathy that is
rapidly becoming the most common cause of hepatocellular carcinoma worldwide. The …

Signaling pathways allow cells to detect and respond to a wide variety of chemical (eg Ca2+
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …

Photopharmacology is an emerging approach in drug design and pharmacological therapy.
Light is used to switch a pharmacophore between a biologically inactive and an active …

Metabolic diseases, such as obesity, Type II diabetes and hepatic steatosis, are a significant
public health concern affecting more than half a billion people worldwide. The prevalence of …

Simple Summary Breast cancer is the leading cause of cancer-related deaths in the female
population, with estrogen receptor (ER)-positive breast cancer accounting for two-third of …

Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-
inflammatory effects. The purpose of this study was to explore the mechanism underlying …

Background: The platinum (II) complexes as anticancer agents have been well explored for
the development of novel analogs. Yet, none of them achieved clinical importance in …

This review provides an updated account on the current methods, principles and mechanism
of action of therapies for the detection of molecular markers of therapeutic importance in the …

The development of fluorescent probes based on the skeletal structure of small-molecule
targeted anticancer drugs is promising for biomedical applications because these probes …

Adverse impacts associated with the interactions of numerous endocrine‐disruptor
chemicals (EDCs) with estrogen receptor 1 play a pivotal role in reproductive dysfunction …