Major depression is a significant medical issue impacting millions of individuals worldwide.
Identifying factors contributing to its manifestation has been a subject of intense investigation …

Both the neuropsychiatric syndrome of apathy and major depressive disorder comprise a
heterogenous cluster of symptoms which span multiple behavioural domains. Despite this …

Depression is one of the main diseases that lead to disability and loss of ability to work. As a
traditional Chinese medicine, Zhi-zi-chi decoction is utilized to regulate and improve …

Objective Early life stressors are well-established risk factors for psychiatric disorders, and
evidence also suggests that these promote vulnerability to epilepsy. Given the high …

Studies in human and non‐human species suggest that decision‐making behaviour can be
biased by an affective state, also termed an affective bias. To study these behaviours in non …

Though excess salt intake is well-accepted as a dietary risk factor for cardiovascular
diseases, relatively little has been explored about how it impacts behavior, despite the …

The judgement bias test represents one of the most applied tools to evaluate animals'
optimistic/pessimistic attitude and to infer their emotional and welfare state accordingly. The …

Alcohol use disorder (AUD) is one of the most common, but still poorly treated, psychiatric
conditions. Developing new treatments requires a better understanding of the aetiology of …

Given the important role of brain-derived neurotrophic factor (BDNF)-mediated Trkβ
signalling in the mechanism of action of antidepressants (ADs), we examined ligand …

Major depressive disorder (MDD) is a globally prevalent, complex disorder with a wide
range of symptoms. Current-line antidepressants are only effective in minority of patients …