[HTML][HTML] Future of colorectal cancer screening: from one-size-fits-all to tailor-made

T Kortlever, M van der Vlugt, E Dekker - Frontiers in Gastroenterology, 2022 - frontiersin.org
Screening for colorectal cancer (CRC) and its precursor lesions, advanced adenomas (AA),
has been shown to effectively reduce CRC-related mortality. However, the method of CRC …

[HTML][HTML] Feasibility of quantification based on novel evaluation with stool DNA and fecal immunochemical test for colorectal cancer detection

H Xu, H Chen, J Hu, Z Xiong, D Li, S Wang, J Yu - BMC gastroenterology, 2022 - Springer
Abstract Background Stool DNA (sDNA) tests and fecal immunochemical test (FIT) are used
for the detection of colorectal cancer (CRC). Here we performed a novel evaluation using …

[HTML][HTML] Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival

JW Villanueva, L Kwong, T Han, SA Martinez… - Bmc Genomics, 2022 - Springer
Somatic mutations drive colorectal cancer (CRC) by disrupting gene regulatory
mechanisms. Distinct combinations of mutations can result in unique changes to regulatory …

[HTML][HTML] A novel stool methylation test for the non-invasive screening of gastric and colorectal cancer

L Ma, J Gong, M Zhao, X Kong, P Gao, Y Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Because of poor compliance or low sensitivity, existing diagnostic approaches
are unable to provide an efficient diagnosis of patients with gastric and colorectal cancer …

Evaluation of combined detection of multigene mutation and SDC2/SFRP2 methylation in stool specimens for colorectal cancer early diagnosis

J Lin, L Zhang, M Chen, J Chen, Y Wu, T Wang… - International Journal of …, 2022 - Springer
Purpose Molecular diagnostics of colorectal cancer (CRC) can be used as an auxiliary
approach for patients recommended for colonoscopy, providing more CRC supplemental …

Identification of multi-omic biomarkers from Fecal DNA for improved Detection of Colorectal Cancer and precancerous lesions

Y Fang, J Peng, Z Li, R Jiang, Y Lin, Y Shi, J Sun… - MedRxiv, 2022 - medrxiv.org
Background Timely diagnosis and intervention of colorectal cancer (CRC) at curable stages
is essential for improving patient survival. Stool samples carry exfoliation of intestinal …

[HTML][HTML] Novel multiplex stool-based assay for the detection of early-stage colon cancer in a Chinese population

HH Jiang, SW Xing, X Tang, Y Chen, K Lin… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Stool DNA (sDNA) methylation analysis is a promising, noninvasive
approach for colorectal cancer screening; however, reliable biomarkers for detecting early …