Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
[HTML][HTML] Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …
disorder that manifests in genetically susceptible women following a range of negative …
[HTML][HTML] Obesity and risk of female reproductive conditions: A Mendelian randomisation study
SS Venkatesh, T Ferreira, S Benonisdottir… - PLoS …, 2022 - journals.plos.org
Background Obesity is observationally associated with altered risk of many female
reproductive conditions. These include polycystic ovary syndrome (PCOS), abnormal uterine …
reproductive conditions. These include polycystic ovary syndrome (PCOS), abnormal uterine …
Causes and consequences of polycystic ovary syndrome: insights from Mendelian randomization
T Zhu, MO Goodarzi - The Journal of Clinical Endocrinology & …, 2022 - academic.oup.com
Context Although polycystic ovary syndrome (PCOS) is the most common endocrinopathy
affecting women of reproductive age, risk factors that may cause the syndrome are poorly …
affecting women of reproductive age, risk factors that may cause the syndrome are poorly …
[HTML][HTML] Polycystic ovary syndrome: a “risk-enhancing” factor for cardiovascular disease
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women
of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic …
of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic …
[PDF][PDF] A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes
Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using
data from large endometriosis and EOC genome-wide association meta-analyses, we …
data from large endometriosis and EOC genome-wide association meta-analyses, we …
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation
Background: Some individuals living with obesity may be relatively metabolically healthy,
whilst others suffer from multiple conditions that may be linked to adverse metabolic effects …
whilst others suffer from multiple conditions that may be linked to adverse metabolic effects …
[HTML][HTML] Criteria for diagnosis of polycystic ovary syndrome during adolescence: literature review
Polycystic ovary syndrome (PCOS) is one of the most common endocrine conditions in
women. PCOS may be more challenging to diagnose during adolescence due to an overlap …
women. PCOS may be more challenging to diagnose during adolescence due to an overlap …
[HTML][HTML] Why are women with polycystic ovary syndrome obese?
TM Barber - British Medical Bulletin, 2022 - ncbi.nlm.nih.gov
Introduction: Polycystic ovary syndrome (PCOS) is a common condition characterized by
reproductive, hyperandrogenic and dysmetabolic features, and often becomes clinically …
reproductive, hyperandrogenic and dysmetabolic features, and often becomes clinically …
[HTML][HTML] Sex hormone candidate gene polymorphisms are associated with endometriosis
I Golovchenko, B Aizikovich, O Golovchenko… - International Journal of …, 2022 - mdpi.com
The present study was designed to examine whether sex hormone polymorphisms proven
by GWAS are associated with endometriosis risk. Unrelated female participants totaling …
by GWAS are associated with endometriosis risk. Unrelated female participants totaling …