The field of immuno-oncology is now at the forefront of cancer care and is rapidly evolving.
The immune checkpoint blockade has been demonstrated to restore antitumor responses in …

Simple Summary Prostate cancer is a heterogenous disease in terms of disease
aggressiveness and therapy response, leading to dilemmas in treatment decisions. This …

Recent technological development in spatial transcriptomics allows researchers to measure
gene expression of cells and their spatial locations at the almost single-cell level, which …

Tumor heterogeneity and cellular plasticity are key determinants of tumor progression,
metastatic spread, and therapy response driven by the cancer stem cell (CSC) population …

Recent advances in spatially resolved transcriptomics (SRT) have revolutionized biological
and medical research and enabled unprecedented insight into the functional organization …

当今, 数字技术作为一种新型的健康决定因素, 它改变了社会, 经济, 城市和家庭,
进而又影响了人类健康; 人类进入了一个全新的数字虚拟世界. 由此, 在大数据生态流行病学理论 …

Advances in multiplex immunofluorescence (mIF) and digital image analysis has enabled
simultaneous assessment of protein defects in electron transport chain components …

Identification of novel and known cell types with single cell RNA-seq (scRNA-seq) is
revolutionising the study of multicellular organisms. However, typical scRNA-seq analysis …

Spatial transcriptomics (ST) holds the promise to identify the existence and extent of spatial
variation of gene expression in complex tissues. Such analyses could help identify gene …

Nowadays, digital technology has become a new type of health determinant, which not only
changes society, economy, city and family, but also affects human health; human beings …