[HTML][HTML] Regulatory role of apoptotic and inflammasome related proteins and their possible functional aspect in thiram associated tibial dyschondroplasia of poultry

MFA Kulyar, W Yao, Q Mo, Y Ding, Y Zhang, J Gao, K Li… - Animals, 2022 - mdpi.com
Simple Summary Tibial dyschondroplasia (TD) is a metabolic disorder that impairs bony and
cartilage processes. It is common in broilers due to the consumption of thiram, especially in …

[HTML][HTML] Thiram induces myocardial oxidative damage and apoptosis in broilers via interfering their cardiac metabolism

Q Mo, MFA Kulyar, Y Ding, Y Zhang, H Pan… - … and Environmental Safety, 2022 - Elsevier
Thiram is a dithiocarbamate pesticide extensively used as a fungicide to preserve crops and
seeds. Long-term exposure to thiram causes potential harm to the health of human beings …

Chlorogenic acid suppresses miR-460a in the regulation of Bcl-2, causing interleukin-1β reduction in thiram exposed chondrocytes via caspase-3/caspase-7 pathway

MFA Kulyar, Q Mo, W Yao, Y Ding, Z Yan, H Du, H Pan… - Phytomedicine, 2022 - Elsevier
Background Apoptosis is thought to be involved in all processes, including normal cell cycle,
immune system, atrophy, embryonic development, and chemical-induced cellular damage …

[HTML][HTML] CD147 Promotes Tumorigenesis via Exosome-Mediated Signaling in Rhabdomyosarcoma

A Fahs, N Hussein, H Zalzali, F Ramadan… - Cells, 2022 - mdpi.com
Rhabdomyosarcoma (RMS) is an aggressive childhood soft-tissue tumor, with propensity for
local invasion and distant metastasis. Exosomes are secreted vesicles that mediate …

Protective effects of maslinic acid on high fat diet-induced liver injury in mice

T Li, H Wang, S Dong, M Liang, J Ma, XW Jiang, W Yu - Life Sciences, 2022 - Elsevier
Aims Due to the prevalence of high-fat diets and lack of exercise, diseases related to nutrient
metabolism such as nonalcoholic fatty liver disease (NAFLD) have become one of the …

Chlorogenic acid suppresses mitochondrial apoptotic effectors Bax/Bak to counteract Nod‐like receptor pyrin domain 3 (NLRP3) inflammasome in thiram exposed …

MFA Kulyar, W Yao, Y Ding, H Du, Q Mo, H Pan… - Phytomedicine, 2022 - Elsevier
Background Tibial dyschondroplasia (TD) is a common disease characterized by
proliferation and the deterioration of growth plate's chondrocytes due to widespread …

The toxicity of cooking oil fumes on human bronchial epithelial cells through ROS‐mediated MAPK, NF‐κB signaling pathways and NLRP3 inflammasome

J Liu, M Fu, J Miao, Y Sun, R Zhu, C Liu… - Environmental …, 2022 - Wiley Online Library
Cooking oil fumes (COFs) are the main pollutants in kitchen and indoor air, which threaten
human health. Exposure to COFs may lead to respiratory diseases and impair pulmonary …

Elevated mir-145-5p is associated with skeletal muscle dysfunction and triggers apoptotic cell death in C2C12 myotubes

J Jin, F Li, C Fan, Y Wu, C He - Journal of Muscle Research and Cell …, 2022 - Springer
Skeletal muscle dysfunction is a common comorbidity of chronic obstructive pulmonary
disease (COPD), and the molecular mechanisms regarding to the pathogenesis of this …

Excess Iron added to the diet induces the apoptosis of chicken's liver through the PI3KAKT mTOR axis

F Sun, Y An, X Lv, N Sun, X Lv, C Liu, X Gao - 2022 - researchsquare.com
Iron (Fe), an essential trace element, plays a key role in biological metabolism. The
PI3K/AKT/mTOR axis plays an important role in the control of apoptosis. However, the effect …