Current perspectives: evidence to date on BTK inhibitors in the management of multiple sclerosis
E Carnero Contentti, J Correale - Drug Design, Development and …, 2022 - Taylor & Francis
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
leading to demyelination and neurodegeneration. Basic and translational studies have …
leading to demyelination and neurodegeneration. Basic and translational studies have …
Thyroid hormone-dependent oligodendroglial cell lineage genomic and non-genomic signaling through integrin receptors
R Emamnejad, M Dass, M Mahlis, S Bozkurt… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a heterogeneous autoimmune disease whereby the pathological
sequelae evolve from oligodendrocytes (OLs) within the central nervous system and are …
sequelae evolve from oligodendrocytes (OLs) within the central nervous system and are …
Continued P2X7 activation leads to mitochondrial fission and compromising microglial phagocytosis after subarachnoid haemorrhage
T Tao, X Chen, Y Zhou, Q Zheng, S Gao… - Journal of …, 2022 - Wiley Online Library
Subarachnoid haemorrhage (SAH) has a high rate of disability and mortality. Extremely
damaging molecules, including adenosine triphosphate (ATP), are released from …
damaging molecules, including adenosine triphosphate (ATP), are released from …
The extracellular matrix proteins tenascin-C and tenascin-R retard oligodendrocyte precursor maturation and myelin regeneration in a cuprizone-induced long-term …
J Bauch, A Faissner - Cells, 2022 - mdpi.com
Oligodendrocytes are the myelinating cells of the central nervous system. The physiological
importance of oligodendrocytes is highlighted by diseases such as multiple sclerosis, in …
importance of oligodendrocytes is highlighted by diseases such as multiple sclerosis, in …
Histological and top-down proteomic analyses of the visual pathway in the cuprizone demyelination model
MSM Almuslehi, MK Sen, PJ Shortland… - Journal of Molecular …, 2022 - Springer
A change in visual perception is a frequent early symptom of multiple sclerosis (MS), the
pathoaetiology of which remains unclear. Following a slow demyelination process caused …
pathoaetiology of which remains unclear. Following a slow demyelination process caused …
Lanthionine Ketimine ethyl Ester accelerates Remyelination in a mouse model of multiple sclerosis
Although over 20 disease modifying therapies are approved to treat Multiple Sclerosis (MS),
these do not increase remyelination of demyelinated axons or mitigate axon damage …
these do not increase remyelination of demyelinated axons or mitigate axon damage …
Age-related changes in microglia of the rat spinal cord
EA Kolos, DE Korzhevskii - Journal of Evolutionary Biochemistry and …, 2022 - Springer
The aim of this study was to evaluate age-related changes in microglial cells in various
regions of the cervical spinal cord in young (4 months) and aging (18 months) rats using …
regions of the cervical spinal cord in young (4 months) and aging (18 months) rats using …
Oligodendroglial primary cilium heterogeneity during development and demyelination/remyelination
G Delfino, K Bénardais, J Graff, B Samama… - Frontiers in Cellular …, 2022 - frontiersin.org
The primary cilium (PC) has emerged as an indispensable cellular antenna essential for
signal transduction of important cell signaling pathways. The rapid acquisition of knowledge …
signal transduction of important cell signaling pathways. The rapid acquisition of knowledge …
[PDF][PDF] Zinc finger protein Zfp276 is a novel transcriptional regulator driving oligodendroglial differentiation by inhibition of immaturity factors
T Aberle - 2022 - opus4.kobv.de
Fast saltatory nerve conduction relies on myelin sheaths which isolate axons and are
produced by myelinating oligodendrocytes in the central nervous system. Oligodendrocytes …
produced by myelinating oligodendrocytes in the central nervous system. Oligodendrocytes …
ВОЗРАСТНЫЕ ИЗМЕНЕНИЯ МИКРОГЛИИ СПИННОГО МОЗГА КРЫС
ЕА Колос, ДЭ Коржевский - Российский физиологический журнал им …, 2022 - elibrary.ru
Целью настоящего исследования явилась оценка изменений микроглии в различных
областях шейного отдела спинного мозга (СМ) молодых (4 мес.) и стареющих (18 мес.) …
областях шейного отдела спинного мозга (СМ) молодых (4 мес.) и стареющих (18 мес.) …