TGF‐β Signaling: A Recap of SMAD‐independent and SMAD‐dependent Pathways

S Aashaq, A Batool, SA Mir, MA Beigh… - Journal of cellular …, 2022 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) is a proinflammatory cytokine known to control a
diverse array of pathological and physiological conditions during normal development and …

The Role of SMAD4 Inactivation in Epithelial–Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?

ML Racu, L Lebrun, AA Schiavo, C Van Campenhout… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is currently one of the
deadliest cancers. Despite the progress that has been made in the research of patient care …

Evolution and diversity of TGF-β pathways are linked with novel developmental and behavioral traits

WS Lo, M Roca, M Dardiry, M Mackie… - Molecular Biology …, 2022 - academic.oup.com
Transforming growth factor-β (TGF-β) signaling is essential for numerous biologic functions.
It is a highly conserved pathway found in all metazoans including the nematode …

Transcriptome profiling of male and female Ascaris lumbricoides reproductive tissues

O Phuphisut, A Poodeepiyasawat, T Yoonuan… - Parasites & …, 2022 - Springer
Background Ascaris lumbricoides causes human ascariasis, the most prevalent helminth
disease, infecting approximately 1 billion individuals globally. In 2019 the global disease …

Reciprocal interactions between transforming growth factor beta signaling and collagens: Insights from Caenorhabditis elegans

MB Goodman, C Savage‐Dunn - Developmental Dynamics, 2022 - Wiley Online Library
Studies in genetically tractable organisms such as the nematode Caenorhabditis elegans
have led to pioneering insights into conserved developmental regulatory mechanisms. For …

Identification and functional analysis of two drosophila mothers against decapentaplegic protein (Smad) genes and their involvement in immune responses in the red …

YM Zhang, CY Lin, BZ Li, WR Dong, MA Shu - Fish & Shellfish Immunology, 2022 - Elsevier
Drosophila mothers against decapentaplegic proteins (Smads), the crucial signal
transducers in activating downstream gene transcription through transforming growth factor …

[HTML][HTML] KLF16 promotes pancreatic adenocarcinoma cell proliferation and migration by positively regulating SMAD6

W Mi, Z Zheng, JD Lu, SQ Duan, J Zhang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Pancreatic adenocarcinoma (PAAD) is a cancerous tumor with an
extremely poor 5-year survival rate. The exploration of biomarkers for the diagnosis and …

[HTML][HTML] The feedback regulator Nord controls Dpp/BMP signaling via extracellular interaction with Dally in the Drosophila wing

T Akiyama, CW Seidel, MC Gibson - Developmental Biology, 2022 - Elsevier
Abstract The Drosophila BMP 2/4 homologue Decapentaplegic (Dpp) acts as a morphogen
to regulate diverse developmental processes, including wing morphogenesis …

[图书][B] Telomerase Reverse Transcriptase Marks a Novel Population of Adult Stem Cells in the Mouse Brain That Respond to Metabolic Interventions by Modulating …

GS Jensen - 2022 - search.proquest.com
Telomerase reverse transcriptase (TERT) is expressed by quiescent adult stem cells (qASC)
in numerous adult murine and human tissues but has never been explored in the adult …

Intraperitoneal injection of 17β‐estradiol increases ovarian smad2/3 expression in Yangtze sturgeon Acipenser dabryanus

H Yue, H Ye, R Ruan, H Du, Q Wei… - Aquaculture …, 2022 - Wiley Online Library
Smad (mothers against decapentaplegic homologue) proteins are the downstream
signalling factors involved in TGFβ (transforming growth factor beta) pathways. The present …