The sirtuin family in health and disease

QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Theophylline: Old drug in a new light, application in COVID-19 through computational studies

LM Montaño, B Sommer, JC Gomez-Verjan… - International Journal of …, 2022 - mdpi.com
Theophylline (3-methyxanthine) is a historically prominent drug used to treat respiratory
diseases, alone or in combination with other drugs. The rapid onset of the COVID-19 …

Anthocyanins inhibit airway inflammation by downregulating the NF-κB pathway via the miR-138-5p/SIRT1 axis in asthmatic mice

Y Liu, M Zhang, H Zhang, X Qian, L Luo… - International Archives of …, 2022 - karger.com
Objective: Asthma, caused by chronic inflammation, is a common disease. Anthocyanins are
involved in asthma treatment. This study explored the mechanism of anthocyanins on airway …

Roles of sirtuins in asthma

Y Liu, G Shi - Respiratory research, 2022 - Springer
Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent lysine deacylases and
deacetylases that participate in a variety of cellular processes, including transcriptional …

Sirt5 Inhibits BmNPV Replication by Promoting a Relish-Mediated Antiviral Pathway in Bombyx mori

M Zhang, S Fei, J Xia, Y Wang, H Wu, X Li… - Frontiers in …, 2022 - frontiersin.org
Silent information regulators (Sirtuins) belong to the family of nicotinamide adenine
dinucleotide (NAD+)-dependent histone deacetylases (HDACs) that have diverse functions …

Renalase Challenges the Oxidative Stress and Fibroproliferative Response in COVID‐19

D Stojanovic, M Stojanovic, J Milenkovic… - Oxidative Medicine …, 2022 - Wiley Online Library
The hallmark of the coronavirus disease 2019 (COVID‐19) pathophysiology was reported to
be an inappropriate and uncontrolled immune response, evidenced by activated …

The role of viral infections in pulmonary exacerbations of patients with non-cystic fibrosis bronchiectasis: A systematic review

E Kartsiouni, S Chatzipanagiotou, P Tamvakeras… - Respiratory …, 2022 - Elsevier
Background Bronchiectasis is a cause of increased morbidity of the respiratory system.
Exacerbations among patients with non-CF (cystic fibrosis) bronchiectasis result in reduced …

The Interrelationship Between Persistent Asthma and Atopy in Children

R Pouyanfar, M Mansouri… - …, 2022 - immunoreg.shahed.ac.ir
Background: Childhood asthma is mainly developed by an interplay between genetic and
environmental factors. Atopic asthma has been regarded as the most common form of …