Annual Research Review: The transdiagnostic revolution in neurodevelopmental disorders

DE Astle, J Holmes, R Kievit… - Journal of Child …, 2022 - Wiley Online Library
Practitioners frequently use diagnostic criteria to identify children with neurodevelopmental
disorders and to guide intervention decisions. These criteria also provide the organising …

Modelling the neurodevelopmental pathogenesis in neuropsychiatric disorders. Bioactive kynurenines and their analogues as neuroprotective agents—in celebration …

M Tanaka, E Spekker, Á Szabó, H Polyák… - Journal of Neural …, 2022 - Springer
Following introduction of the monoamine oxidase type B inhibitor selegiline for the treatment
of Parkinson's disease (PD), discovery of the action mechanism of Alzheimer's disease …

Genomic architecture of autism from comprehensive whole-genome sequence annotation

B Trost, B Thiruvahindrapuram, AJS Chan… - Cell, 2022 - cell.com
Fully understanding autism spectrum disorder (ASD) genetics requires whole-genome
sequencing (WGS). We present the latest release of the Autism Speaks MSSNG resource …

The Lancet Commission on the future of care and clinical research in autism

C Lord, T Charman, A Havdahl, P Carbone… - The Lancet, 2022 - thelancet.com
Executive summary Affecting about 78 million people worldwide, autism is a condition of
global importance because of its prevalence and the degree to which it can affect individuals …

Annual Research Review: Translational machine learning for child and adolescent psychiatry

D Dwyer, N Koutsouleris - Journal of Child Psychology and …, 2022 - Wiley Online Library
Children and adolescents could benefit from the use of predictive tools that facilitate
personalized diagnoses, prognoses, and treatment selection. Such tools have not yet been …

Therapeutic applications of transcutaneous auricular vagus nerve stimulation with potential for application in neurodevelopmental or other pediatric disorders

S Zhu, X Zhang, M Zhou, KM Kendrick… - Frontiers in …, 2022 - frontiersin.org
Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) as a newly
developed technique involves stimulating the cutaneous receptive field formed by the …

Characterizing the ASD–ADHD phenotype: Measurement structure and invariance in a clinical sample

AD Krakowski, KT Cost, P Szatmari… - Journal of Child …, 2022 - Wiley Online Library
Background Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder
(ADHD) have considerable overlap, supporting the need for a dimensional framework that …

[HTML][HTML] Novel treatments for autism spectrum disorder based on genomics and systems biology

D Baribeau, E Anagnostou - Pharmacology & therapeutics, 2022 - Elsevier
Background Autism spectrum disorder (ASD) is a highly heterogeneous
neurodevelopmental disorder with a complex underlying genetic architecture. There are …

Characterizing creative thinking and creative achievements in relation to symptoms of attention-deficit/hyperactivity disorder and autism spectrum disorder

M Stolte, V Trindade-Pons, P Vlaming, B Jakobi… - Frontiers in …, 2022 - frontiersin.org
Previous research on ADHD and ASD has mainly focused on the deficits associated with
these conditions, but there is also evidence for strengths. Unfortunately, our understanding …

Using smartphone app use and lagged-ensemble machine learning for the prediction of work fatigue and boredom

D Lekkas, GD Price, NC Jacobson - Computers in human behavior, 2022 - Elsevier
Intro As smartphone usage becomes increasingly prevalent in the workplace, the physical
and psychological implications of this behavior warrant consideration. Recent research has …