Mechanics and functional consequences of nuclear deformations

Y Kalukula, AD Stephens, J Lammerding… - … reviews Molecular cell …, 2022 - nature.com
As the home of cellular genetic information, the nucleus has a critical role in determining cell
fate and function in response to various signals and stimuli. In addition to biochemical …

[HTML][HTML] Production of cultured meat from pig muscle stem cells

H Zhu, Z Wu, X Ding, MJ Post, R Guo, J Wang, J Wu… - Biomaterials, 2022 - Elsevier
Cultured meat is meat for consumption produced in a more sustainable way. It involves cell
harvesting and expansion, differentiation into myotubes, construction into muscle fibres and …

Cellular and molecular pathways controlling muscle size in response to exercise

M Attwaters, SM Hughes - The FEBS journal, 2022 - Wiley Online Library
From the discovery of ATP and motor proteins to synaptic neurotransmitters and growth
factor control of cell differentiation, skeletal muscle has provided an extreme model system …

Effect of boron-doped mesoporous bioactive glass nanoparticles on C2C12 cell viability and differentiation: potential for muscle tissue application

D Ege, Q Nawaz, AM Beltrán… - … Biomaterials Science & …, 2022 - ACS Publications
Mesoporous bioactive glasses (MBGs) exhibit a high surface area and a highly ordered
mesoporous structure. MBGs have potential for both hard and soft tissue engineering …

Brush-induced orientation of collagen fibers in layer-by-layer nanofilms: A simple method for the development of human muscle fibers

MH Iqbal, FJR Revana, E Pradel, V Gribova… - ACS …, 2022 - ACS Publications
The engineering of skeletal muscle tissue, a highly organized structure of myotubes, is
promising for the treatment of muscle injuries and muscle diseases, for replacement, or for …

[HTML][HTML] Appreciating the role of cell shape changes in the mechanobiology of epithelial tissues

M Luciano, M Versaevel, E Vercruysse, A Procès… - Biophysics …, 2022 - pubs.aip.org
The wide range of epithelial cell shapes reveals the complexity and diversity of the
intracellular mechanisms that serve to construct their morphology and regulate their …

Micro-patterned cell populations as advanced pharmaceutical drugs with precise functional control

H Che, M Selig, B Rolauffs - Advanced Drug Delivery Reviews, 2022 - Elsevier
Human cells are both advanced pharmaceutical drugs and 'drug deliverers'. However,
functional control prior to or after cell implantation remains challenging. Micro-patterning …

3D interfacial and spatiotemporal regulation of human neuroepithelial organoids

C Tang, X Wang, M D'Urso, C van der Putten… - Advanced …, 2022 - Wiley Online Library
Neuroepithelial (NE) organoids with dorsal–ventral patterning provide a useful three‐
dimensional (3D) in vitro model to interrogate neural tube formation during early …

Twinfilin-1 is an essential regulator of myogenic differentiation through the modulation of YAP in C2C12 myoblasts

MT Nguyen, YH Won, TW Kwon, W Lee - Biochemical and biophysical …, 2022 - Elsevier
Actin cytoskeletal dynamics play a critical role in the regulation of myogenesis through
mechanotransduction, Hippo signaling modulation, cell proliferation, and morphological …

Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo

W Nahaboo, SE Eski, E Despin‐Guitard… - The EMBO …, 2022 - embopress.org
Mesoderm arises at gastrulation and contributes to both the mouse embryo proper and its
extra‐embryonic membranes. Two‐photon live imaging of embryos bearing a keratin …