Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials
Spinal cord injury is a severely disabling neurological condition leading to impaired mobility,
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
Molecular mechanisms and clinical application of multipotent stem cells for spinal cord injury
M Szymoniuk, J Litak, L Sakwa, A Dryla, W Zezuliński… - Cells, 2022 - mdpi.com
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …
psychosocial sequelae. The majority of patients after SCI suffer from permanent disability …
Prognostic factors for cervical spinal cord injury without major bone injury in elderly patients
H Nakajima, N Yokogawa, T Sasagawa… - Journal of …, 2022 - liebertpub.com
In the current aging society, there has been a marked increase in the incidence of cervical
spinal cord injury (CSCI) without major bone injury. This multi-center study aimed to identify …
spinal cord injury (CSCI) without major bone injury. This multi-center study aimed to identify …
Early vs late surgical decompression for central cord syndrome
JH Badhiwala, JR Wilson, JS Harrop, AR Vaccaro… - JAMA …, 2022 - jamanetwork.com
Importance The optimal clinical management of central cord syndrome (CCS) remains
unclear; yet this is becoming an increasingly relevant public health problem in the face of an …
unclear; yet this is becoming an increasingly relevant public health problem in the face of an …
Spinal cord bioelectronic interfaces: opportunities in neural recording and clinical challenges
L Jiang, B Woodington… - Journal of Neural …, 2022 - iopscience.iop.org
Bioelectronic stimulation of the spinal cord has demonstrated significant progress in the
restoration of motor function in spinal cord injury (SCI). The proximal, uninjured spinal cord …
restoration of motor function in spinal cord injury (SCI). The proximal, uninjured spinal cord …
Earlier surgery reduces complications in acute traumatic thoracolumbar spinal cord injury: analysis of a multi-center cohort of 4108 patients
M Balas, MP Guttman, JH Badhiwala… - Journal of …, 2022 - liebertpub.com
Early surgical intervention to decompress the spinal cord and stabilize the spinal column in
patients with acute traumatic thoracolumbar spinal cord injury (TLSCI) may lessen the risk of …
patients with acute traumatic thoracolumbar spinal cord injury (TLSCI) may lessen the risk of …
[HTML][HTML] Ultra-early spinal decompression surgery can improve neurological outcome of complete cervical spinal cord injury; a systematic review and meta-analysis
M Yousefifard, B Hashemi… - Archives of academic …, 2022 - ncbi.nlm.nih.gov
Methods: A search was performed in Medline, Embase, Scopus and Web of Science
electronic databases, until the end of August 2021. Cohort studies and clinical trials were …
electronic databases, until the end of August 2021. Cohort studies and clinical trials were …
Decreased adiponectin levels are a risk factor for cognitive decline in spinal cord injury
F Liu, H Xu, Y Yin, Y Chen, L Xie, H Li… - Disease …, 2022 - Wiley Online Library
Objective. Spinal cord injury (SCI) has become popular in recent years, and cognitive
decline is a common complication. Adiponectin is a common protein hormone involved in …
decline is a common complication. Adiponectin is a common protein hormone involved in …
A functional outcome prediction model of acute traumatic spinal cord injury based on extreme gradient boost
Z Sizheng, H Boxuan, X Feng, Z Dianying - Journal of orthopaedic surgery …, 2022 - Springer
Objective We aimed to construct a nonlinear regression model through Extreme Gradient
Boost (XGBoost) to predict functional outcome 1 year after surgical decompression for …
Boost (XGBoost) to predict functional outcome 1 year after surgical decompression for …