Shiga Toxin-Producing Escherichia coli and Milk Fat Globules

A Bagel, D Sergentet - Microorganisms, 2022 - mdpi.com
Shiga toxin-producing Escherichia coli (STEC) are zoonotic Gram-negative bacteria. While
raw milk cheese consumption is healthful, contamination with pathogens such as STEC can …

[HTML][HTML] Timing is everything: impact of development, ageing and circadian rhythm on macrophage functions in urinary tract infections

AS Wang, NJ Steers, AR Parab, F Gachon… - Mucosal …, 2022 - Elsevier
The bladder supports a diversity of macrophage populations with functional roles related to
homeostasis and host defense, including clearance of cell debris from tissue, immune …

Safety, pharmacokinetic, and pharmacodynamic study of sibofimloc, a novel FimH blocker in patients with active Crohn's disease

W Reinisch, X Hébuterne, A Buisson… - Journal of …, 2022 - Wiley Online Library
Abstract Background and Aim Expression of FimH adhesin by invasive Escherichia coli in
the gastrointestinal tract of patients with Crohn's disease (CD) facilitates binding to epithelial …

Pseudomonas aeruginosa in Cancer Therapy: Current Knowledge, Challenges and Future Perspectives

Z Pang, MD Gu, T Tang - Frontiers in Oncology, 2022 - frontiersin.org
Drug resistance, undesirable toxicity and lack of selectivity are the major challenges of
conventional cancer therapies, which cause poor clinical outcomes and high mortality in …

Polysaccharides from Vaccaria segetalis seeds reduce urinary tract infections by inhibiting the adhesion and invasion abilities of uropathogenic Escherichia coli

R Yao, X Mao, Y Xu, X Qiu, L Zhou, Y Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
The seeds of Vaccaria segetalis (Neck.) are from a traditional medicinal plant Garcke, also
called Wang-Bu-Liu-Xing in China. According to the Chinese Pharmacopoeia, the seeds of …

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14

K Tomasek, A Leithner, I Glatzova, MS Lukesch… - Elife, 2022 - elifesciences.org
A key attribute of persistent or recurring bacterial infections is the ability of the pathogen to
evade the host's immune response. Many Enterobacteriaceae express type 1 pili, a pre …

[HTML][HTML] Salmonella fimbrial protein StcD induces cyclooxygenase-2 expression via Toll-like receptor 4

K Uchiya, S Isono, M Yoshimura, T Wajima… - Journal of Microbiology …, 2022 - Elsevier
Abstract Introduction The genome of Salmonella enterica serovar Typhimurium contains 13
operons with homology to fimbrial genes. Methods To investigate the involvement of these …

[PDF][PDF] A year of microbiota and IBD—Highlights and advances

W Arras, S Koentgen, H Ceuleers… - Microb. Health …, 2022 - microbiotajournal.com
The role of gut microbiota in the pathogenesis and disease course of IBD continues to gain
increasing scientific interest. This review highlights important advances in the field via …