Theranostic nanoparticles with disease-specific administration strategies

P Zhang, Y Li, W Tang, J Zhao, L Jing, KJ McHugh - Nano Today, 2022 - Elsevier
Recent advances in the synthesis of nanomaterials with diagnostic and therapeutic
capabilities have been rapidly reshaping the landscape of precision medicine. Impressive …

Theranostic nanomedicines for the treatment of cardiovascular and related diseases: current strategies and future perspectives

N Manners, V Priya, AK Mehata, M Rawat, S Mohan… - Pharmaceuticals, 2022 - mdpi.com
Cardiovascular and related diseases (CVRDs) are among the most prevalent chronic
diseases in the 21st century, with a high mortality rate. This review summarizes the various …

Hetero-Multivalent Targeted Liposomal Drug Delivery to Treat Pseudomonas aeruginosa Infections

A Singla, SB Simbassa, B Chirra… - … Applied Materials & …, 2022 - ACS Publications
Pseudomonas aeruginosa is the leading nosocomial and community-acquired pathogen
causing a plethora of acute and chronic infections. The Centers for Disease Control and …

[HTML][HTML] Comprehensive comparison of theranostic nanoparticles in breast cancer

A Nikdouz, N Namarvari, RG Shayan… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Breast cancer is the most frequently happening cancer and the most typical cancer death
among females. Despite the crucial progress in breast cancer therapy by using …

Review on emergence of nanomaterial coatings in bio-engineered cardiovascular stents

P Shah, S Chandra - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Nanotechnology is envisaged to provide a dynamic approach to treat blocking of the
coronary arteries that occurs due to resistance to the normal blood flow to the heart …

The transplantation of rapamycin-treated senescent human mesenchymal stem cells with enhanced proangiogenic activity promotes neovascularization and ischemic …

Y Cao, W Chen, Q Lei, F Gao, W Ren, L Chen… - Acta Pharmacologica …, 2022 - nature.com
Few therapies can reverse the proangiogenic activity of senescent mesenchymal
stromal/stem cells (MSCs). In this study, we investigated the effects of rapamycin on the …

Dual coating of chitosan and albumin negates the protein corona-induced reduced vascular adhesion of targeted PLGA microparticles in human blood

G Lopez-Cazares, O Eniola-Adefeso - Pharmaceutics, 2022 - mdpi.com
Vascular-targeted carriers (VTCs) have the potential to localize therapeutics and imaging
agents to inflamed, diseased sites. Poly (lactic-co-glycolic acid)(PLGA) is a negatively …

Shape-specific microfabricated particles for biomedical applications: a review

TL Moore, AB Cook, E Bellotti, R Palomba… - Drug Delivery and …, 2022 - Springer
The storied history of controlled the release systems has evolved over time; from degradable
drug-loaded sutures to monolithic zero-ordered release devices and nano-sized drug …

Clot-Targeted Enzyme-Responsive Nanoparticles for Thrombolytic Therapy

M Sun - 2022 - search.proquest.com
Vascular pathologies, such as myocardial infarction, stroke, and pulmonary embolism, are
major causes of morbidities and mortalities in the US and globally. A primary event in such …

The Effect of Surface Modification of PLGA Drug Carriers on Vascular Wall Adhesion and Plasma Protein Corona for Improved Vascular Targeting

G Lopez - 2022 - deepblue.lib.umich.edu
Vascular-targeted drug delivery requires the successful localization and adhesion of drug
carriers to diseased sites via biomarkers, such as inflammation. Poly (lactic-co-glycolic …