mRNA-based therapies: Preclinical and clinical applications
M Qureischi, J Mohr, E Arellano-Viera… - International Review of …, 2022 - Elsevier
At the fundamental level, messenger RNA (mRNA)-based therapeutics involves the delivery
of in vitro-transcribed (IVT) mRNA into the cytoplasm of a target cell, where it is translated …
of in vitro-transcribed (IVT) mRNA into the cytoplasm of a target cell, where it is translated …
Historical DNA Manipulation Overview
L Montoliu - Applications of Genome Modulation and Editing, 2022 - Springer
The history of DNA manipulation for the creation of genetically modified animals began in
the 1970s, using viruses as the first DNA molecules microinjected into mouse embryos at …
the 1970s, using viruses as the first DNA molecules microinjected into mouse embryos at …
Advances and Applications of Transgenesis in Farm Animals
TR Talluri, BP Telugu - Frontier Technologies in Bovine Reproduction, 2022 - Springer
Modification of animal genomes is an age-old tradition rooted in selective breeding of
genetic outlier animals over successive generations for enhancing production traits …
genetic outlier animals over successive generations for enhancing production traits …
Cytoplasmic Microinjection of piggyBac Transposase mRNA and Transposon Vectors for Efficient In Vitro Production of Transgenic Porcine Parthenotes
R Miyagasako, J Hansol, S Watanabe, K Miyoshi… - OBM Genetics, 2022 - lidsen.com
The efficient production of transgenic (Tg) piglets has remained a challenge in the field of
domestic animal studies. Unlike mice, the pronuclei of pig zygotes cannot be easily studied …
domestic animal studies. Unlike mice, the pronuclei of pig zygotes cannot be easily studied …