Fast and accurate Ab Initio Protein structure prediction using deep learning potentials

R Pearce, Y Li, GS Omenn, Y Zhang - PLoS computational biology, 2022 - journals.plos.org
Despite the immense progress recently witnessed in protein structure prediction, the
modeling accuracy for proteins that lack sequence and/or structure homologs remains to be …

Accelerating therapeutic protein design

M ElGamacy - Advances in Protein Chemistry and Structural Biology, 2022 - Elsevier
Protein structures provide for defined microenvironments that can support complex
pharmacological functions, otherwise unachievable by small molecules. The advent of …

Structure-function analysis of a Group II Intron reverse transcriptase

JM Alvarado Torres - 2022 - repositories.lib.utexas.edu
Mobile group II introns are ribozymes and mobile genetic elements found in all branches of
life. They consist of a highly structured intron RNA that encodes a reverse transcriptase (RT) …