Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

Development of the gastrointestinal tract in newborns as a challenge for an appropriate nutrition: a narrative review

F Indrio, J Neu, M Pettoello-Mantovani, F Marchese… - Nutrients, 2022 - mdpi.com
The second and third trimesters of pregnancy are crucial for the anatomical and functional
development of the gastrointestinal (GI) tract. If premature birth occurs, the immaturity of the …

Interventions to prevent bronchopulmonary dysplasia in preterm neonates: an umbrella review of systematic reviews and meta-analyses

T Abiramalatha, VV Ramaswamy… - JAMA …, 2022 - jamanetwork.com
Importance Bronchopulmonary dysplasia (BPD) has multifactorial etiology and long-term
adverse consequences. An umbrella review enables the evaluation of multiple proposed …

Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants

MR Asbury, S Shama, JY Sa, N Bando, J Butcher… - Cell Host & Microbe, 2022 - cell.com
Nutrient fortifiers are added to human milk to support the development of very-low-birth-
weight infants. Currently, bovine-milk-based fortifiers (BMBFs) are predominantly …

Evaluation of risk and preventive factors for necrotizing enterocolitis in premature newborns. A systematic review of the literature

AM Campos-Martinez, J Expósito-Herrera… - Frontiers in …, 2022 - frontiersin.org
Necrotizing enterocolitis (NEC) is a serious condition related to prematurity and the initiation
of enteral feeding. In this article, we review the evidence published in recent years on …

Associations of maternal milk feeding with neurodevelopmental outcomes at 7 years of age in former preterm infants

MB Belfort, E Knight, S Chandarana, E Ikem… - JAMA network …, 2022 - jamanetwork.com
Importance Maternal milk feeding may have unique long-term neurodevelopmental benefits
in very preterm infants. Objective To examine the extent to which maternal milk feeding after …

Early-life factors associated with neurobehavioral outcomes in preterm infants during NICU hospitalization

T Zhao, T Griffith, Y Zhang, H Li, N Hussain, B Lester… - Pediatric …, 2022 - nature.com
Background The aim of this study was to investigate the influence of early-life pain/stress
and medical characteristics on neurobehavioral outcomes in preterm infants. Methods A …

Human milk and preterm infant brain development: a narrative review

MB Belfort, TE Inder - Clinical therapeutics, 2022 - Elsevier
Purpose To review and synthesize the literature on human milk and structural brain
development and injury in preterm infants, focusing on the application of quantitative brain …

Milk exosomal microRNAs: postnatal promoters of β cell proliferation but potential inducers of β cell de-differentiation in adult life

BC Melnik, G Schmitz - International Journal of Molecular Sciences, 2022 - mdpi.com
Pancreatic β cell expansion and functional maturation during the birth-to-weaning period is
driven by epigenetic programs primarily triggered by growth factors, hormones, and nutrients …

US state policies for Medicaid coverage of donor human milk

AT Rose, ER Miller, M Butler, C Eden, JH Kim… - Journal of …, 2022 - nature.com
Donor human milk is recommended by the American Academy of Pediatrics for high-risk
infants when mother's own milk is absent or insufficient in quantity. Several factors may …