[HTML][HTML] More than meets the eye: The role of microglia in healthy and diseased retina

E Murenu, MJ Gerhardt, M Biel… - Frontiers in …, 2022 - frontiersin.org
Microglia are the main resident immune cells of the nervous system and as such they are
involved in multiple roles ranging from tissue homeostasis to response to insults and circuit …

The genetic basis for adult onset glaucoma: recent advances and future directions

Z Wang, JL Wiggs, T Aung, AP Khawaja… - Progress in Retinal and …, 2022 - Elsevier
Glaucoma, a diverse group of eye disorders that results in the degeneration of retinal
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …

Clusterin, other extracellular chaperones, and eye disease

MR Wilson, S Satapathy, S Jeong, ME Fini - Progress in Retinal and eye …, 2022 - Elsevier
Proteostasis refers to all the processes that maintain the correct expression level, location,
folding and turnover of proteins, essential to organismal survival. Both inside cells and in …

[HTML][HTML] MicroRNA profiles in aqueous humor between pseudoexfoliation glaucoma and normal tension glaucoma patients in a Korean population

H Cho, H Seong, C Kee, DH Song, SJ Kim, SW Seo… - Scientific Reports, 2022 - nature.com
We aimed to obtain microRNA (miRNA) profiles of patients with pseudoexfoliation (PEX)
glaucoma or normal-tension glaucoma (NTG) compared to normal controls using individual …

[HTML][HTML] Emerging roles of oxidative stress in the pathogenesis of pseudoexfoliation syndrome

S Mastronikolis, M Pagkalou… - Experimental and …, 2022 - spandidos-publications.com
Pseudoexfoliation syndrome (PEXS) is a systemic disease caused by defects in the
extracellular matrix (ECM) remodelling process leading to the chronic deposition of …

[HTML][HTML] RNA sequencing of lens capsular epithelium implicates novel pathways in Pseudoexfoliation syndrome

S Mullany, H Marshall, T Zhou… - … & visual science, 2022 - iovs.arvojournals.org
Purpose: Pseudoexfoliation syndrome (PEX) is a common systemic disease that results in
severe and often irreversible vision loss. Despite considerable research effort, PEX remains …

[HTML][HTML] Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function

T Rosell-García, S Rivas-Muñoz, A Colige… - International Journal of …, 2022 - mdpi.com
Members of the lysyl oxidase (LOX) family catalyze the oxidative deamination of lysine and
hydroxylysine residues in collagen and elastin in the initiation step of the formation of …

Increased desmosine in the lens capsules is associated with augmented elastin turnover in pseudoexfoliation syndrome

M Rebecca, K Sripriya, M Bharathselvi… - Experimental Eye …, 2022 - Elsevier
Pseudoexfoliation syndrome (PXF) is an idiopathic disease with a high prevalence rate. The
elastosis disorder is contributed by genetic and non-genetic factors. Elastin dysregulation …

Is pseudoexfoliation syndrome associated with vitreoretinal interface abnormalities?

SK Adıyeke, N Kutlu, K Özen, MA Doran… - Graefe's Archive for …, 2022 - Springer
Background To evaluate vitreoretinal interface abnormalities in patients with
pseudoexfoliation (PEX) syndrome. Methods This case–control study was performed in 136 …

The Effect of Amniotic Membrane Transplantation on Trabeculectomy in Patients with Pseudoexfoliation Glaucoma

H Kim, S Moon, J Kim, J Lee - Journal of Ophthalmology, 2022 - Wiley Online Library
Purpose. The aim is to evaluate the effect of amniotic membrane transplantation (AMT) on
trabeculectomy with mitomycin C in patients with pseudoexfoliation glaucoma (PXG) …