Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …

Exosomes are endosome-derived microvesicles that carry cell-specific biological cargo,
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …

Deficient bone regeneration causes bone defects or nonunion in a substantial proportion of
trauma patients that urges for novel therapies. To develop a reliable therapy, we …

Osteoporosis, characterized by bone mineral density reduction, bone mass loss, increased
bone fragility, and propensity to fractures, is a common disease in older individuals and one …

Although bone is an organ that displays potential for self-healing after damage, bone
regeneration does not occur properly in some cases, and it is still a challenge to treat large …

Dental implant restoration is the preferred choice for patients with dentition defects or
edentulous patients, and obtaining stable osseointegration is the determining factor for …

Bone grafts have traditionally come from four sources: the patients' own tissue (autograft),
tissue from a living or cadaveric human donor (allograft), animal donors (xenograft) and …

Gene therapy is one of the most promising approaches in regenerative medicine. Gene-
activated matrices provide stable gene expression and the production of osteogenic proteins …

We developed an innovative method to include quercetin into alpha-calcium sulphate
hemihydrate/nano-hydroxyapatite (α-CSH/n-HA), to prepare a novel quercetin-containing α …

Poly (l-lactide-co-caprolactone)(PLCL) electrospun scaffolds with seeded stem cells have
drawn great interest in tissue engineering. This study investigated the biological behavior of …