Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

Metastatic breast cancer cells disseminate to organs with a soft microenvironment. Whether
and how the mechanical properties of the local tissue influence their response to treatment …

Cancer cells are known for their ability to adapt variable metabolic programs depending on
the availability of specific nutrients. Our previous studies have shown that uptake of fatty …

Alzheimer's disease (AD), the most common form of dementia, has increasing incidence,
increasing mortality rates, and poses a huge burden on healthcare. None of the currently …

Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial
dynamics and is known to play an important role in numerous pathophysiological processes …

Aging is by far the most prominent risk factor for Alzheimer's disease (AD), and both aging
and AD are associated with apparent metabolic alterations. As developing effective …

Macrophage/microglial modulation plays a critical role in the pathogenesis of multiple
sclerosis (MS), which is an inflammatory disorder of the central nervous system. Dynamin …

Previous studies have demonstrated dysregulated mitochondrial dynamics in fibrotic livers
and hepatocytes. Little is currently known about how mitochondrial dynamics are involved …

Excessive alcohol consumption can lead to alterations in brain structure and function, even
causing irreversible learning and memory disorders. The hippocampus is one of the most …