As the most potent professional antigen presenting cells, dendritic cells (DCs) have the
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …

The emergence of immunotherapy as a new pillar of cancer treatment is due to the success
of immune checkpoint blockade drugs. However, many patients receiving checkpoint …

The aim of dendritic cell (DC) vaccination in cancer is to induce tumor-specific effector T
cells that may reduce and control tumor mass. Immunostimulants that could drive a desired …

Colorectal cancer (CRC) is the third most common cancer and the third leading cause of
cancer mortality in the United States (US) as well as in Europe [1]. CRC incidence and …

Preferred embodiments are directed to method of augmenting ability of dendritic cells to
stimulate NK cell and/or T cell activity comprising incubating said dendritic cells with a …

Preferred embodiments are directed to methods of prevention, ameliorating or reversing
type 1 diabetes com prising the steps of: a) selecting a patient in need of treatment; b) …

US20220387516A1 - Fibroblast-derived universal immunological composition - Google Patents
US20220387516A1 - Fibroblast-derived universal immunological composition - Google Patents …

Disclosed are populations of dendritic cells generated from stem cells capable of inducing
immunity towards cancer. In one embodiment said dendritic cells are generated from …

Disclosed are methods, means and compositions of matter useful for treatment of heart
failure, and/or post infarct pathological remodeling using ex vivo reprogrammed immune …

BACKGROUND [0001] There is an increasing prevalence of cancer in human and its
significant contribution to mortality means there is a continuing need for new therapies …