We review the current knowledge of pancreas pathology in type 1 diabetes. During the last
two decades, dedicated efforts toward the recovery of pancreas from deceased patients with …

Background Erectile dysfunction (ED), as one of the most prevalent consequences in male
diabetic patients, has a serious impact on men's physical and mental health, and the …

Diabetes mellitus (DM) is among the chronic metabolic disorders that its incidence rate has
shown an increase in developed and wealthy countries due to lifestyle and obesity. The …

Resistance to regeneration of insulin-producing pancreatic β cells is a fundamental
challenge for type 1 and type 2 diabetes. Recently, small molecule inhibitors of the kinase …

Abstract Objective Type 1 diabetes (T1D) is characterized by autoimmune-associated β-cell
loss, insulin insufficiency, and hyperglycemia. Although TNFα signaling is associated with β …

Background aims To explore the long-term safety and benefit of umbilical cord
mesenchymal stromal cell (MSCs) plus autologous bone marrow mononuclear cell (aBM …

The pharmaceutical industry develops, manufactures, and markets medicines and drugs,
and is an indispensable part of healthcare sectors. Millions of patients with life-threatening …

Abstract Type 2 diabetes (T2D) is a global health problem caused primarily due to the
inability of pancreatic beta-cells to secrete adequate amounts of insulin during insulin …

When differentially expressed genes are detected from samples containing different types of
cells, only a very coarse overview without any cell type-specific information is obtained …

Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by the immune-mediated
destruction of insulin-producing pancreatic beta cells. However, the canonical notion that …