[HTML][HTML] Mechanisms of cisplatin resistance in HPV negative head and neck squamous cell carcinomas

AB Griso, L Acero-Riaguas, B Castelo… - Cells, 2022 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are the eighth most common cancers
worldwide. While promising new therapies are emerging, cisplatin-based chemotherapy …

[HTML][HTML] A novel neutrophil extracellular trap signature to predict prognosis and immunotherapy response in head and neck squamous cell carcinoma

Q Li, W Chen, Q Li, J Mao, X Chen - Frontiers in Immunology, 2022 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant
cancers, and patients with HNSCC possess early metastases and poor prognosis …

[HTML][HTML] Advances in highly active one-carbon metabolism in cancer diagnosis, treatment and drug resistance: a systematic review

S Liu, ZM Wang, DM Lv, YX Zhao - Frontiers in Oncology, 2022 - frontiersin.org
Study background objectives Cancer poses a significant health concern as it is incurable.
Every year, research on how to treat and eradicate this chronic condition is done. This …

Senolytic-mediated elimination of head and neck tumor cells induced into senescence by cisplatin

F Ahmadinejad, T Bos, B Hu, E Britt, J Koblinski… - Molecular …, 2022 - ASPET
Therapeutic outcomes achieved in head and neck squamous cell carcinoma (HNSCC)
patients by concurrent cisplatin-based chemoradiotherapy initially reflect both tumor …

Cost-effectiveness of pembrolizumab for the first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma in the United States

RH Borse, K Ramakrishnan, J Gandhi… - Journal of Medical …, 2022 - Taylor & Francis
Aims Pembrolizumab, as monotherapy in first-line recurrent or metastatic (R/M) head and
neck squamous cell carcinoma (HNSCC) with a combined positive score (CPS)≥ 1 and in …

Reirradiation of recurrent and second primary cancers of the head and neck: a review of the contemporary evidence

PJ Kreinbrink, LM Lewis, KP Redmond… - Current Treatment Options …, 2022 - Springer
Opinion statement Recurrent and second primary head and neck cancers represent a
clinical challenge due to frequently unresectable and/or locally advanced disease. Given …

Current status of systemic therapy in head and neck cancer

A Mittal, A Sharma - Journal of Chemotherapy, 2022 - Taylor & Francis
There are several controversies in the management of head and neck cancer (SCCHN).
Although combined modality treatment is standard in locally advanced SCCHN (LA …

Is fractionated robotic stereotactic body radiosurgery optional salvage treatment for the re-irradiation of locally recurrent nasopharyngeal carcinoma?

O Dogan, G Yaprak, H Ozyurt… - Journal of Cancer …, 2022 - search.ebscohost.com
Abstract < bold> Purpose: </bold> Recurrent nasopharyngeal carcinoma (NPC)
after previous radiation therapy is a significant problem. This study was to determine the …

[PDF][PDF] Electrochemotherapy as palliative treatment in patients with recurrent and/or metastatic head and neck tumours: features analysis for an early determination of …

F Maglitto, G Salzano, F Longo… - European Review for …, 2022 - researchgate.net
OBJECTIVE: The aim of this study was to identify features mainly involved in determining the
partial response (PR) to the Electrochemotherapy (ECT) in patients with recurrent and/or …

Efficacy and toxicity of weekly paclitaxel, carboplatin, and cetuximab as induction chemotherapy or in cases of metastases or relapse for head and neck cancer with a …

R Forman, H Deshpande, B Burtness… - Head & Neck, 2022 - Wiley Online Library
Background Paclitaxel, carboplatin, and cetuximab (PCC) has shown promise as induction
chemotherapy and in patients with metastatic/recurrent head and neck cancer (HNC). Given …