Mitochondrial DNA repair in neurodegenerative diseases and ageing
V Bazzani, M Equisoain Redin, J McHale… - International Journal of …, 2022 - mdpi.com
Mitochondria are the only organelles, along with the nucleus, that have their own DNA.
Mitochondrial DNA (mtDNA) is a double-stranded circular molecule of~ 16.5 kbp that can …
Mitochondrial DNA (mtDNA) is a double-stranded circular molecule of~ 16.5 kbp that can …
Therapeutic applications of mitochondrial transplantation
This review aims to make a framework of exogenous healthy mitochondrial transplantation
and to assemble present information for improving new therapeutic applications in a variety …
and to assemble present information for improving new therapeutic applications in a variety …
[HTML][HTML] Mosaic dysfunction of mitophagy in mitochondrial muscle disease
Mitophagy is a quality control mechanism that eliminates damaged mitochondria, yet its
significance in mammalian pathophysiology and aging has remained unclear. Here, we …
significance in mammalian pathophysiology and aging has remained unclear. Here, we …
The complicated nature of somatic mtDNA mutations in aging
M Sanchez-Contreras, SR Kennedy - Frontiers in aging, 2022 - frontiersin.org
Mitochondria are the main source of energy used to maintain cellular homeostasis. This
aspect of mitochondrial biology underlies their putative role in age-associated tissue …
aspect of mitochondrial biology underlies their putative role in age-associated tissue …
Strategies to improve the efficiency of somatic cell nuclear transfer
Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …
Physical fitness and its correlation with handgrip strength in active community-dwelling older adults
PJ Pan, NW Hsu, MJ Lee, YY Lin, CC Tsai, WS Lin - Scientific Reports, 2022 - nature.com
In this cross-sectional study, we assessed the physical fitness levels of active community-
dwelling older adults. Moreover, we investigated the correlation of their (stratified by age and …
dwelling older adults. Moreover, we investigated the correlation of their (stratified by age and …
Incidence and risk factors of metabolic syndrome among Royal Thai Army personnel
B Sakboonyarat, R Rangsin, MA Mittleman - Scientific Reports, 2022 - nature.com
Metabolic Syndrome is a clustering of obesity, hyperglycemia/insulin resistance,
dyslipidemia, and hypertension. We aimed to determine the incidence of metabolic …
dyslipidemia, and hypertension. We aimed to determine the incidence of metabolic …
Accurate age estimation from blood samples of Han Chinese individuals using eight high-performance age-related CpG sites
X Han, C Xiao, S Yi, Y Li, M Chen, D Huang - International Journal of Legal …, 2022 - Springer
Age-related CpG sites (AR-CpGs) are currently the most promising biomarkers for forensic
age estimation. In our previous studies, we first validated the age correlation of seven …
age estimation. In our previous studies, we first validated the age correlation of seven …
Dietary restriction modulates mitochondrial DNA damage and oxylipin profile in aged rats
AP Gureev, NV Andrianova, IB Pevzner… - The FEBS …, 2022 - Wiley Online Library
Age‐related impairment of coordination of the processes of maintaining mitochondrial
homeostasis is associated with a decrease in the functionality of cells and leads to …
homeostasis is associated with a decrease in the functionality of cells and leads to …
Biochemical analyses for dental age estimation: a review
M Pillalamarri, R Manyam, S Pasupuleti… - Egyptian Journal of …, 2022 - Springer
Background For various legal and forensic scenarios, establishing an individual's age, both
living and dead, plays a crucial role. Various morphological, radiographic, and molecular …
living and dead, plays a crucial role. Various morphological, radiographic, and molecular …