T cell abnormalities in systemic sclerosis

W Jin, Y Zheng, P Zhu - Autoimmunity Reviews, 2022 - Elsevier
Systemic sclerosis (SSc) is an autoimmune disease with a poor prognosis. To date, the
pathogenesis of SSc is still unclear; moreover, its pathological conditions include …

[HTML][HTML] CD4+ Cytotoxic T cells–phenotype, function and transcriptional networks controlling their differentiation pathways

T Preglej, W Ellmeier - Immunology Letters, 2022 - Elsevier
The two major subsets of peripheral T cells are classically divided into the CD4+ T helper
cells and the cytotoxic CD8+ T cell lineage. However, the appearance of some effector …

Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19

N Kaneko, J Boucau, HH Kuo, C Perugino… - Clinical …, 2022 - Elsevier
Many studies have been performed in severe COVID-19 on immune cells in the circulation
and on cells obtained by bronchoalveolar lavage. Most studies have tended to provide …

Distinct disease-specific Tfh cell populations in 2 different fibrotic diseases: IgG4-related disease and Kimura disease

R Munemura, T Maehara, Y Murakami, R Koga… - Journal of Allergy and …, 2022 - Elsevier
Background How T follicular (Tfh) cells contribute to many different B-cell class-switching
events during T-cell–dependent immune responses has been unclear. Diseases with …

Orchestration of immune cells contributes to fibrosis in IgG4-related disease

N Kaneko, M Moriyama, T Maehara, H Chen… - Immuno, 2022 - mdpi.com
This review summarizes recent progress in understanding the pathogenesis of IgG4-related
disease (IgG4-RD), with a focus on fibrosis. Several studies reported that CD4+ T cells with …

Fibrosing mediastinitis in a child with Mendelian susceptibility to mycobacterial disease possibly due to Bacillus Calmette-Guérin

N Sharifinejad, SA Mahdaviani, S Fallah… - Allergy, Asthma & …, 2022 - Springer
Background Mendelian susceptibility to mycobacterial disease (MSMD) is an uncommon
disorder with increased susceptibility to less virulent mycobacteria including bacillus …

[PDF][PDF] T cells with tumor-specific phenotypes largely originate from pericolic lymph nodes in colorectal cancer

NL de Vries - scholarlypublications …
Background Cancer immunotherapies aiming at reactivating anti-tumor T cell responses
have yielded significant clinical benefits. To further improve the success rate of such T cell …