[HTML][HTML] In silico investigation and potential therapeutic approaches of natural products for COVID-19: Computer-aided drug design perspective
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
substantial number of deaths around the world, making it a serious and pressing public …
substantial number of deaths around the world, making it a serious and pressing public …
Prevention, treatment and potential mechanism of herbal medicine for Corona viruses: A review
The pandemic of coronavirus disease 2019 (COVID-19) caused by the SARS-coronavirus 2
(SARS-CoV-2) virus has become the greatest global public health crisis in recent years, and …
(SARS-CoV-2) virus has become the greatest global public health crisis in recent years, and …
Screening of phytochemicals as potent inhibitor of 3-chymotrypsin and papain-like proteases of SARS-CoV2: an in silico approach to combat COVID-19
A Swargiary, S Mahmud, MA Saleh - Journal of Biomolecular …, 2022 - Taylor & Francis
COVID-19 and its causative organism SARS-CoV2 that emerged from Wuhan city, China
have paralyzed the world. With no clinically approved drugs, the global health system is …
have paralyzed the world. With no clinically approved drugs, the global health system is …
Discovery of novel SARS-CoV-2 3CL protease covalent inhibitors using deep learning-based screen
Abstract SARS-CoV-2 3CL protease is one of the key targets for drug development against
COVID-19. Most known SARS-CoV-2 3CL protease inhibitors act by covalently binding to …
COVID-19. Most known SARS-CoV-2 3CL protease inhibitors act by covalently binding to …
[HTML][HTML] Virtual screening and molecular dynamics simulation analysis of Forsythoside A as a plant-derived inhibitor of SARS-CoV-2 3CLpro
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a more severe strain of
coronavirus (CoV) that was first emerged in China in 2019. Available antiviral drugs could …
coronavirus (CoV) that was first emerged in China in 2019. Available antiviral drugs could …
Natural biflavones are potent inhibitors against SARS-CoV-2 papain-like protease
L Li, L Ma, Y Hu, X Li, M Yu, H Shang, Z Zou - Phytochemistry, 2022 - Elsevier
Papain-like protease (PL pro) is a key enzyme encoded by SARS-CoV-2 that is essential for
viral replication and immune evasion. Significant suppression of viral spread and promotion …
viral replication and immune evasion. Significant suppression of viral spread and promotion …
Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins
Zika virus (ZIKV) is a dangerous human pathogen and no antiviral drugs have been
approved to date. The chalcones are a group of small molecules that are found in a number …
approved to date. The chalcones are a group of small molecules that are found in a number …
[HTML][HTML] Natural and semi-synthetic flavonoid anti-SARS-CoV-2 agents for the treatment of long COVID-19 disease and neurodegenerative disorders of cognitive …
The aim of this review is to highlight the beneficial attributes of flavonoids, a diverse family of
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …
Recent developments of flavonoids with various activities
ZG Sun, ZN Li, JM Zhang, XY Hou… - Current Topics in …, 2022 - ingentaconnect.com
Flavonoids, a series of compounds with a C6-C3-C6 structure, mostly originate from plant
metabolism. Flavonoids have shown beneficial effects on many aspects of human …
metabolism. Flavonoids have shown beneficial effects on many aspects of human …
Therapeutic journey and recent advances in the synthesis of coumarin derivatives
Background: Coumarin is an oxygen-containing compound in medicinal chemistry.
Coumarin plays an important role in both natural systems like plants and synthetic medicinal …
Coumarin plays an important role in both natural systems like plants and synthetic medicinal …