Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

S Popat, P Baas, C Faivre-Finn, N Girard… - Annals of …, 2022 - annalsofoncology.org
Incidence of malignant pleural mesothelioma (MPM) is generally higher in males than
females and is attributed to historical differences in exposures with world-standardised …

An update on emerging therapeutic options for malignant pleural mesothelioma

A Davis, H Ke, S Kao, N Pavlakis - Lung Cancer: Targets and …, 2022 - Taylor & Francis
The treatment paradigm for malignant pleural mesothelioma (MPM) has changed little in the
last 18 years. Radical intent treatment, consisting of surgical resection, radiotherapy and …

Management of advanced pleural mesothelioma—at the crossroads

AK Nowak, A Jackson, C Sidhu - JCO Oncology Practice, 2022 - ascopubs.org
The management of pleural mesothelioma has changed with the demonstration that first-line
checkpoint blockade therapy improves survival. This review covers issues of relevance to …

Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma

J Creaney, AM Patch, V Addala, SA Sneddon… - Genome medicine, 2022 - Springer
Background Malignant pleural mesothelioma (MPM) has a poor overall survival with few
treatment options. Whole genome sequencing (WGS) combined with the immune features of …

[HTML][HTML] Multimodal therapy of epithelioid pleural mesothelioma: improved survival by changing the surgical treatment approach

LV Klotz, H Hoffmann, R Shah, F Eichhorn… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Background The exact role and type of surgery for malignant pleural mesothelioma (MPM)
remains controversial. This study aimed at analyzing a 20-year single center perioperative …

Extrapleural pneumonectomy versus pleurectomy/decortication for malignant pleural mesothelioma

N Zhou, DC Rice, AS Tsao, PP Lee… - The Annals of Thoracic …, 2022 - Elsevier
Background Whether extrapleural pneumonectomy (EPP) or extended pleurectomy/
decortication (P/D) is the optimal resection for malignant pleural mesothelioma remains …

Current management and future perspective in pleural mesothelioma

R Shah, LV Klotz, J Glade - Cancers, 2022 - mdpi.com
Simple Summary Platin-based chemotherapy with pemetrexed has been the backbone of
meaningful treatment in pleural mesothelioma for the last 16 years, alongside vinorelbine …

Novel insights into mesothelioma therapy: emerging avenues and future prospects

L Kuryk, G Rodella, M Staniszewska, KW Pancer… - Frontiers in …, 2022 - frontiersin.org
Malignant mesothelioma is a rare and aggressive cancer that develops in the thin layer
surrounding the mesothelium and is mainly caused by asbestos exposure. Despite …

The evolving therapeutic landscape for malignant pleural mesothelioma

ND Perera, AS Mansfield - Current oncology reports, 2022 - Springer
Abstract Purpose of Review For patients with malignant pleural mesothelioma, prognosis is
poor with extremely low 5-year survival rates and limited therapeutic options. Here, we …

Splicing deregulation, microRNA and notch aberrations: fighting the three-headed dog to overcome drug resistance in malignant mesothelioma

DP Anobile, G Montenovo, C Pecoraro… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction Malignant mesothelioma (MMe) is an aggressive rare cancer of the
mesothelium, associated with asbestos exposure. MMe is currently an incurable disease at …