The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …

It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Objective TIGIT/CD155 has attracted widespread attention as a new immune checkpoint and
a potential target for cancer immunotherapy. In our study, we evaluated the role of …

Esculetin is a coumarin compound, which belongs to the class of benzopyrone enriched in
various plants such as Sonchus grandifolius, Aesculus turbinata, etc. Free radicals lead to …

NF-κB is generally recognized as an important regulator of ageing, through its roles in
cellular senescence and inflammatory pathways. Activated in virtually all cell-cell …

Catechins are a cluster of polyphenolic bioactive components in green tea. Anticarcinogenic
effects of tea catechins have been reported since the 1980s, but it has been controversial …

Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Withaferin A is a C28 steroidal lactone derived from the plant Withania somnifera, commonly
known as Ashwagandha. Withaferin A has received great attention for its anticancer …

The ability to develop novel medications based on nanoscale complexes has greatly
enhanced the capabilities of current pharmaceuticals and has made multidimensional …

Aging is a complex process indicated by low energy levels, declined physiological activity,
stress induced loss of homeostasis leading to the risk of diseases and mortality. Recent …