Background Multiple clinical trials with different exercise protocols have demonstrated
efficacy in the management of migraine. However, there is no head-to-head comparison of …

Introduction: The endocannabinoid (eCB) system plays a key role in maintaining
homeostasis, including the regulation of metabolism and stress responses. Chronic stress …

(1) Background: The psychoactive and non-psychoactive constituents of cannabis, Δ9-
tetrahydrocannabinol (THC) and cannabidiol (CBD), synergistically reduce allodynia in …

Spinal cord injury (SCI) is a complex neurophysiological disorder, which can result in many
long-term complications including changes in mobility, bowel and bladder function …

The brain and peripheral nervous system provide oversight to muscle physiology and
metabolism. Muscle is the largest organ in the body and critical for glucose sensitivity …

Endocannabinoid (eCB) signaling is markedly decreased in the hippocampus (Hip) of aged
mice, and the genetic deletion of the cannabinoid receptor type 1 (CB1) leads to an early …

Resistance training–based exercise is commonly prescribed in the clinic for the treatment of
chronic pain. Mechanisms of aerobic exercise for analgesia are frequently studied, while …

Chronic pain states are highly prevalent and yet poorly controlled by currently available
analgesics. It has been reported that enriched environment (EE), as a new way of …

Pain is the most common reason for a physician visit, which accounts for a considerable
proportion of the global burden of disease and greatly affects patients' quality of life …

Chronic pain is a significant health care issue affecting over 100 million Americans with
musculoskeletal pain prevalent in 13-47% of the population. Musculoskeletal pain …