Metabotropic glutamate (mGlu) receptors, a family of G-protein-coupled receptors, have
been identified as novel therapeutic targets based on extensive research supporting their …

Understanding risk factors for substance use disorders (SUD) can facilitate medication
development for SUD treatment. While a rich literature exists discussing environmental …

Neurodevelopmental anomalies are thought to play a crucial role in the emergence of
schizophrenia. The Roman high-avoidance (RHA) rats exhibit impaired prepulse inhibition …

Social withdrawal is one of the most relevant negative symptoms of schizophrenia. Animal
models that mimic schizophrenia's symptoms, in general, and negative symptoms, in …

Initial contact with alcohol generally occurs during adolescence, and high consumption
during this period is associated with increased risk for later alcohol (AUDs) and/or substance …