The broader sense of nonsense
ED Karousis, O Mühlemann - Trends in biochemical sciences, 2022 - cell.com
The term 'nonsense-mediated mRNA decay'(NMD) was initially coined to describe the
translation-dependent degradation of mRNAs harboring premature termination codons …
translation-dependent degradation of mRNAs harboring premature termination codons …
Nonsense-mediated mRNA decay, a finely regulated mechanism
F Lejeune - Biomedicines, 2022 - mdpi.com
Nonsense-mediated mRNA decay (NMD) is both a mechanism for rapidly eliminating
mRNAs carrying a premature termination codon and a pathway that regulates many genes …
mRNAs carrying a premature termination codon and a pathway that regulates many genes …
DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production
Y Uchihara, TBM Permata, H Sato… - Molecular cell, 2022 - cell.com
Antigen presentation by the human leukocyte antigen (HLA) on the cell surface is critical for
the transduction of the immune signal toward cytotoxic T lymphocytes. DNA damage …
the transduction of the immune signal toward cytotoxic T lymphocytes. DNA damage …
Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance
LP Schlautmann, JW Lackmann, J Altmüller… - Nucleic acids …, 2022 - academic.oup.com
The exon junction complex (EJC) is an RNA-binding multi-protein complex with critical
functions in post-transcriptional gene regulation. It is deposited on the mRNA during splicing …
functions in post-transcriptional gene regulation. It is deposited on the mRNA during splicing …