Metronidazole (MNZ) is a nitroimidazole derivative antibiotic that has been generally used in
the treatment of rosacea. However, it has low molecular weight and lipophilicity, limiting the …

Persistent fungal infections caused by biofilms seriously endanger human health. In this
study, a photosensitizer‐polypeptide conjugate (PPa‐cP) comprising a photosensitizer …

Topical conveyance of antifungal agents like itraconazole ITZ has been giving good grounds
for expecting felicitous antifungal medicines. The defiance of topical delivery of this poorly …

Cabotegravir (CAB) is an antiretroviral therapy (ARV) used for Human Immunodeficiency
Virus (HIV) treatment. CAB has low solubility, which affects its bioavailability in oral therapy …

Primaquine (PMQ) is an effective antimalaria drug with several limitations. We report the
combinatorial approach of thermoresponsive hydrogels and Dermarollers® for transdermal …

Valsartan (VAL) is a BCS class II drug with low solubility and high permeability and, thus, its
formulations often encounter low bioavailability problems. Its low bioavailability can be …

Due to the limitations of oral administration of valsartan, in this study, we aimed to develop
thermosensitive hydrogel for sustained transdermal delivery and improved bioavailability of …

Despite the health benefits of β-carotene, its activity has been hampered by poor aqueous
solubility and low oral bioavailability. Therefore, it is crucial to develop a new approach to …

Bacterial keratitis is an eye infectious disease which became a global concern due to its
impact to visual impairment in worldwide. Cefazolin (CFZ) is the first-line drug for the …

Recently, continuous emergence of resistant bacteria has appeared as one of the most
serious threats to human health. Therefore, systematic exploration of new antibacterial …