Structure, properties of gossypol and its derivatives—from physiological activities to drug discovery and drug design

Y Liu, L Wang, L Zhao, Y Zhang - Natural Product Reports, 2022 - pubs.rsc.org
Covering up to 2022 Gossypol is a polyphenolic compound isolated from cottonseed. There
are two optical enantiomers of gossypol,(−)-gossypol and (+)-gossypol. Gossypol exists as …

Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing Pannexin-1-mediated ferroptosis in db/db mice

J Sun, J Xu, Y Liu, Y Lin, F Wang, Y Han, S Zhang… - 2022 - researchsquare.com
Diabetic cardiomyopathy (DCM) is a serious complication and death cause of diabetes
mellitus (DM). Recent cardiology studies suggest that spermidine has cardioprotective …

Proteomic and metabolomic analyses reveal the novel targets of spermine for alleviating diabetic cardiomyopathy in type II diabetic mice

J Sun, J Xu, Y Liu, X Xu, S Zhang, Y Hao… - Frontiers in …, 2022 - frontiersin.org
Diabetic cardiomyopathy (DCM) is one of the most serious complications of diabetes.
Recent cardiology studies suggest that spermine has cardioprotective effect. Here, we used …