Mitochondria generate ATP and play regulatory roles in various cellular activities. Cancer
cells often exhibit fragmented mitochondria. However, the underlying mechanism remains …

Organisms, including humans, seem to be constantly exposed to various changes, which
often have undesirable effects, referred to as stress. To keep up with these changes …

Inositol plays a significant role in cellular function and signaling. Studies in yeast have
demonstrated an “inositol-less death” phenotype, suggesting that inositol is an essential …

Phospholipid biosynthesis plays a role in mediating membrane-to-histone communication
that influences metabolic decisions. Upon nutrient deprivation, phospholipid methylation …

Secreted acid phosphatases (APases) dephosphorylate extracellular organic phosphate
compounds to supply inorganic phosphate (Pi) to maintain cellular functions. Here, we show …

Inositol is a six-carbon sugar that functions as a precursor for signaling molecules such as
phosphoinositides and inositol polyphosphates, which are involved in the regulation of …

Gene expression is mediated by a series of regulatory proteins, ie, transcription factors.
Under different growth conditions, the transcriptional regulation of structural genes is …

We describe a protocol for measuring phospholipid class and fatty acid composition in the
budding yeast Saccharomyces cerevisiae using a liquid chromatography-mass spectrometry …

過去数百年の間に, 世界的に人類の平均寿命は 2 倍程に延長している. これは医学医術の進歩,
公衆衛生活動の拡大, 食生活の改善や社会保障の充実など様々な社会的な発展に起因した恩恵で …