[HTML][HTML] The sarcoplasmic reticulum of skeletal muscle cells: a labyrinth of membrane contact sites

D Rossi, E Pierantozzi, DO Amadsun, S Buonocore… - Biomolecules, 2022 - mdpi.com
The sarcoplasmic reticulum of skeletal muscle cells is a highly ordered structure consisting
of an intricate network of tubules and cisternae specialized for regulating Ca2+ homeostasis …

[HTML][HTML] Protective role of MG53 against ischemia/reperfusion injury on multiple organs: A narrative review

B Xu, C Wang, H Chen, L Zhang, L Gong… - Frontiers in …, 2022 - frontiersin.org
Ischemia/reperfusion (I/R) injury is a common clinical problem after coronary angioplasty,
cardiopulmonary resuscitation, and organ transplantation, which can lead to cell damage …

[HTML][HTML] A novel homozygous variant in DYSF gene is associated with autosomal recessive limb girdle muscular dystrophy R2/2B

P Spadafora, A Qualtieri, F Cavalcanti… - International Journal of …, 2022 - mdpi.com
Mutations in the DYSF gene, encoding dysferlin, are responsible for Limb Girdle Muscular
Dystrophy type R2/2B (LGMDR2/2B), Miyoshi myopathy (MM), and Distal Myopathy with …

[HTML][HTML] MG53 inhibits necroptosis through ubiquitination-dependent RIPK1 degradation for cardiac protection following ischemia/reperfusion injury

Q Wang, KH Park, B Geng, P Chen, C Yang… - Frontiers in …, 2022 - frontiersin.org
Rationale While reactive oxygen species (ROS) has been recognized as one of the main
causes of cardiac injury following myocardial infarction, the clinical application of …

[HTML][HTML] Deficient Sarcolemma Repair in ALS: A Novel Mechanism with Therapeutic Potential

A Li, J Yi, X Li, L Dong, LW Ostrow, J Ma, J Zhou - Cells, 2022 - mdpi.com
The plasma membrane (sarcolemma) of skeletal muscle myofibers is susceptible to injury
caused by physical and chemical stresses during normal daily movement and/or under …

Recombinant human MG53 protein attenuates brain lesion size in a large animal model of traumatic brain injury

G Jin, JW Ho, TP Keeney-Bonthrone… - Journal of Trauma …, 2022 - journals.lww.com
BACKGROUND MG53, a member of the tripartite motif (TRIM) protein family, plays an
essential role in cell membrane repair and promotes cell survival. Recent studies show that …