Despite the promising advances in novel cancer therapy such as immune checkpoint
inhibitors (ICIs), limitations including therapeutic resistance and toxicity remain. In recent …

Over the last decade, mounting evidence has revealed the key roles of gut microbiota in
modulating the efficacy and toxicity of anticancer drugs, via mechanisms such as …

Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …

Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …

Understanding of the gut microbiome's role in human physiology developed rapidly in recent
years. Moreover, any alteration of this microenvironment could lead to a pathophysiological …

The gut microbiome plays critical roles in human health and disease. Recent studies
suggest it may also be associated with chronic pain and postoperative pain outcomes. In …

Gut microbiota has implications in Central Nervous System (CNS) disorders. Our study
systematically identified preclinical studies aimed to investigate the possible gut microbiota …

Background Gut microbiota has been found involved in neuronal functions and neurological
disorders. Whether and how gut microbiota impacts chronic somatic pain disorders remain …

Dietary patterns contribute to cancer risk. Separately, microbial factors influence the
development of several cancers. However, the interaction of diet and the microbiome and …

Surgical pain is associated with delirium in patients, and acupuncture can treat pain.
However, whether electroacupuncture can attenuate the surgical pain-associated delirium …