Heart disease and stroke statistics—2022 update: a report from the American Heart Association
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
[HTML][HTML] Metabolomics in diabetic retinopathy: from potential biomarkers to molecular basis of oxidative stress
Q Jian, Y Wu, F Zhang - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), the leading cause of blindness in working-age adults, is one of
the most common complications of diabetes mellitus (DM) featured by metabolic disorders …
the most common complications of diabetes mellitus (DM) featured by metabolic disorders …
[PDF][PDF] Insights into modifiable risk factors of cholelithiasis: a Mendelian randomization study
L Chen, H Yang, H Li, C He, L Yang, G Lv - Hepatology, 2022 - Wiley Online Library
Abstract Background and Aims The risk factors of cholelithiasis have not been clearly
identified, especially for total cholesterol. Here, we try to identify these causal risk factors …
identified, especially for total cholesterol. Here, we try to identify these causal risk factors …
[HTML][HTML] Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
Background Type 2 diabetes (T2D) is highly prevalent in British South Asians, yet they are
underrepresented in research. Genes & Health (G&H) is a large, population study of British …
underrepresented in research. Genes & Health (G&H) is a large, population study of British …
[HTML][HTML] Associations of genetically predicted fatty acid levels across the phenome: a mendelian randomisation study
Background Fatty acids are important dietary factors that have been extensively studied for
their implication in health and disease. Evidence from epidemiological studies and …
their implication in health and disease. Evidence from epidemiological studies and …
[HTML][HTML] HNF1A mutations and beta cell dysfunction in diabetes
Y Miyachi, T Miyazawa, Y Ogawa - International journal of molecular …, 2022 - mdpi.com
Understanding the genetic factors of diabetes is essential for addressing the global increase
in type 2 diabetes. HNF1A mutations cause a monogenic form of diabetes called maturity …
in type 2 diabetes. HNF1A mutations cause a monogenic form of diabetes called maturity …
Persistent organic pollutants and β-cell toxicity: a comprehensive review
MP Hoyeck, G Matteo… - American Journal …, 2022 - journals.physiology.org
Persistent organic pollutants (POPs) are a diverse family of contaminants that show
widespread global dispersion and bioaccumulation. Humans are continuously exposed to …
widespread global dispersion and bioaccumulation. Humans are continuously exposed to …
Machine learning-based models for gestational diabetes mellitus prediction before 24–28 weeks of pregnancy: A review
D Mennickent, A Rodríguez, M Farías-Jofré… - Artificial Intelligence in …, 2022 - Elsevier
Abstract Gestational Diabetes Mellitus (GDM) is a hyperglycemia state that impairs maternal
and offspring health, short and long-term. It is usually diagnosed at 24–28 weeks of …
and offspring health, short and long-term. It is usually diagnosed at 24–28 weeks of …
[HTML][HTML] Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data
J Li, C Li, Y Huang, P Guan, D Huang, H Yu… - Journal of Translational …, 2022 - Springer
Ophthalmic epidemiology is concerned with the prevalence, distribution and other factors
relating to human eye disease. While observational studies cannot avoid confounding …
relating to human eye disease. While observational studies cannot avoid confounding …
[HTML][HTML] Interaction of obesity polygenic score with lifestyle risk factors in an electronic health record biobank
Background Genetic and lifestyle factors have considerable effects on obesity and related
diseases, yet their effects in a clinical cohort are unknown. This study in a patient biobank …
diseases, yet their effects in a clinical cohort are unknown. This study in a patient biobank …