The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

Cerebral small vessel disease (CSVD) is the most common chronic vascular disease
involving the whole brain. Great progress has been made in clinical imaging, pathological …

Background and Objectives Cardiovascular risk factors have been implicated in the etiology
of cerebral small vessel disease (CSVD); however, whether the associations are causal …

Background Cardiovascular risk factors are associated with cognitive decline and dementia.
Magnetic resonance imaging provides sensitive measurement of brain morphology and …

Background-Chronic cerebral hypoperfusion (CCH) is an important pathophysiological
mechanism of vascular cognitive impairment (VCI). The heterogeneous effects of CCH …

White matter hyperintensities (WMHs) of presumed vascular origin are one of the most
important neuroimaging markers of cerebral small vessel disease (CSVD), which are closely …

Purpose To study the variation tendency of cerebral small vessel disease (CSVD) imaging
markers and total burden with aging and to research the relationship between aging, CSVD …

We investigated progression and interrelationships of cerebral small vessel disease (cSVD)
markers. This population-based cohort study included 325 participants (age≥ 60 years) …

Cerebral small vessel disease (CSVD) is one of the most important causes of vascular
dementia. Immunosenescence and inflammatory response, with the involvement of the …

Background Subjective cognitive decline (SCD) has been postulated as an early marker of
Alzheimer's Disease (AD) but it can also be associated to other non-AD pathologies such as …