Accurate and timely diagnosis of primary immunodeficiencies (PID) is an ongoing effort.
Individuals with PID can be severely impacted by their disease and many experience …

Background Human echinococcoses are the infection caused by the larval stages of
different species of the genus Echinococcus, mostly E. granulosus and E. multilocularis …

Background Primary immunodeficiencies (PI), which include more than 450 single-gene
inborn errors of immunity and may affect up to 1% of the population, are genetic disorders …

Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …

Background Inborn errors of immunity (IEI) predispose patients to various infectious and non-
infectious complications. Thanks to the development and expanding use of flow cytometry …

Introduction The J Project (JP) physician education and clinical research collaboration
program was started in 2004 and includes by now 32 countries mostly in Eastern and …

Most primary immunodeficiency diseases, and select secondary immunodeficiency
diseases, are treated with immunoglobulin (IG) therapy, administered intravenously or …

Transcription factors are an extremely important group of proteins that are responsible for
the process of selective activation or deactivation of other cellular proteins, usually at the last …

Introduction Primary immunodeficiency diseases (PIDs) are chronic diseases that affect the
various aspects of a patient's life. However, the impact of living with PIDs is poorly described …

We conducted a nationwide survey of inborn errors of immunity (IEI) in Japan for the second
time in 10 years, focusing on protective measures for IEI patients against infectious …