Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase over-expressed in different
solid cancers. In recent years, FAK has been recognized as a new target for the …

Background: Cancer is the first or second leading cause of premature death in 134 of 183
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …

Herein the designed novel benzotriazole-oxadiazole hybrid compounds were synthesized
using both conventional method and ultrasound sonication (US) as an environmentally …

A series of novel β-carboline 1, 3, 4-oxadiazole based hybrids were designed, synthesized,
and tested for cytotoxicity and HDAC inhibition. Among the target compounds, compound …

The oxadiazole core is considered a privileged moiety in many medicinal chemistry
applications. The oxadiazole class includes 1, 2, 3-oxadiazole, 1, 2, 4-oxadiazole, 1, 3, 4 …

Background: Cancer is the second leading cause of death worldwide. Many anticancer
drugs are commercially available, but lack of selectivity, target specificity, cytotoxicity, and …

Heterocyclic nucleus is vital in medicinal chemistry and has allured significant attention in
chemotherapeutic domain. Oxadiazole, a five-membered nitrogen–oxygen-containing …

Cancer is an incredibly diverse and difficult disease to treat, and even after decades of
research there is no definitive cure. Therefore, it is highly crucial to search for novel and new …

Preparation of organic compounds in environmental favor media always a fresh tool in the
synthetic research. If those prepared compounds may possess therapeutically potentiality …

There has been a growing body of studies on benzothiazoles and benzothiazole derivatives
as strong and effective anti-tumor agents against lung, liver, pancreas, breast, and brain …