[HTML][HTML] MicroRNAs in Alzheimer's disease: Potential diagnostic markers and therapeutic targets
S Liu, M Fan, Q Zheng, S Hao, L Yang, Q Xia… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease, with cognitive
decline as the primary clinical feature. According to epidemiological statistics, 50 million …
decline as the primary clinical feature. According to epidemiological statistics, 50 million …
MicroRNAs in kidney injury and disease
N Mahtal, O Lenoir, C Tinel, D Anglicheau… - Nature Reviews …, 2022 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …
[HTML][HTML] MicroRNA let-7 and viral infections: focus on mechanisms of action
A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …
cellular processes, a number of which are involved in host defense mechanisms. In …
The dark side of foetal bovine serum in extracellular vesicle studies
O Urzì, R Olofsson Bagge… - Journal of extracellular …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) have been shown to be involved in cell‐cell communication and
to take part in both physiological and pathological processes. Thanks to their exclusive …
to take part in both physiological and pathological processes. Thanks to their exclusive …
miRNATissueAtlas2: an update to the human miRNA tissue atlas
A Keller, L Gröger, T Tschernig, J Solomon… - Nucleic acids …, 2022 - academic.oup.com
Small non-coding RNAs (sncRNAs) are pervasive regulators of physiological and
pathological processes. We previously developed the human miRNA Tissue Atlas, detailing …
pathological processes. We previously developed the human miRNA Tissue Atlas, detailing …
RNA-based diagnostic markers discovery and therapeutic targets development in cancer
H Wang, Q Meng, J Qian, M Li, C Gu, Y Yang - Pharmacology & …, 2022 - Elsevier
The present review aimed to outline different types of RNAs in cancer diagnostics and
treatment, and to provide novel insights into their clinical applications. RNAs, including …
treatment, and to provide novel insights into their clinical applications. RNAs, including …
[HTML][HTML] From molecular mechanisms to therapeutics: understanding MicroRNA-21 in cancer
J Rhim, W Baek, Y Seo, JH Kim - Cells, 2022 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs that play an important role in regulating
gene expression at a posttranscriptional level. As one of the first discovered oncogenic …
gene expression at a posttranscriptional level. As one of the first discovered oncogenic …
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver
CD Sago, MP Lokugamage, D Loughrey… - Nature biomedical …, 2022 - nature.com
Systemically delivered lipid nanoparticles are preferentially taken up by hepatocytes. This
hinders the development of effective, non-viral means of editing genes in tissues other than …
hinders the development of effective, non-viral means of editing genes in tissues other than …
Omics technologies in allergy and asthma research: An EAACI position paper
U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …
several distinct complex endotypes. Both environmental and genetic factors can influence …
[HTML][HTML] ADAR2 increases in exercised heart and protects against myocardial infarction and doxorubicin-induced cardiotoxicity
X Wu, L Wang, K Wang, J Li, R Chen, X Wu, G Ni… - Molecular Therapy, 2022 - cell.com
Exercise training benefits the heart. The knowledge of post-transcription regulation,
especially RNA editing, in hearts remain rare. ADAR2 is an enzyme that edits adenosine to …
especially RNA editing, in hearts remain rare. ADAR2 is an enzyme that edits adenosine to …