Oxidative stress signaling mediated pathogenesis of diabetic cardiomyopathy
Z Tang, P Wang, C Dong, J Zhang… - … Medicine and Cellular …, 2022 - Wiley Online Library
As a serious cardiovascular complication, diabetic cardiomyopathy (DCM) refers to diabetes‐
related changes in myocardial structure and function, which is obviously different from those …
related changes in myocardial structure and function, which is obviously different from those …
Energy substrate metabolism and oxidative stress in metabolic cardiomyopathy
Metabolic cardiomyopathy is an emerging cause of heart failure in patients with obesity,
insulin resistance, and diabetes. It is characterized by impaired myocardial metabolic …
insulin resistance, and diabetes. It is characterized by impaired myocardial metabolic …
Curcumin attenuates ferroptosis‐induced myocardial injury in diabetic cardiomyopathy through the Nrf2 pathway
Z Wei, Q Shaohuan, K Pinfang… - Cardiovascular …, 2022 - Wiley Online Library
Diabetes causes lipid peroxide to accumulate within cardiomyocytes. Furthermore, lipid
peroxide buildup is a risk factor for ferroptosis. This study is aimed at examining whether …
peroxide buildup is a risk factor for ferroptosis. This study is aimed at examining whether …
Curcumin activates Nrf2/HO‐1 signaling to relieve diabetic cardiomyopathy injury by reducing ROS in vitro and in vivo
X Wu, X Zhou, S Lai, J Liu, J Qi - The FASEB Journal, 2022 - Wiley Online Library
The hallmark feature of Diabetes mellitus (DM) is hyperglycemia which can lead to excess
production of reactive oxygen species (ROS) in the myocardium, contributing to diabetic …
production of reactive oxygen species (ROS) in the myocardium, contributing to diabetic …
The role of mitochondrial abnormalities in diabetic cardiomyopathy
SA Dabravolski, NK Sadykhov, AG Kartuesov… - International Journal of …, 2022 - mdpi.com
Diabetic cardiomyopathy (DCM) is defined as the presence in diabetic patients of abnormal
cardiac structure and performance (such as left ventricular hypertrophy, fibrosis, and …
cardiac structure and performance (such as left ventricular hypertrophy, fibrosis, and …
Interplay of oxidative stress and necrosis-like cell death in cardiac ischemia/reperfusion injury: a focus on necroptosis
A Adameova, C Horvath, S Abdul-Ghani, ZV Varga… - Biomedicines, 2022 - mdpi.com
Extensive research work has been carried out to define the exact significance and
contribution of regulated necrosis-like cell death program, such as necroptosis to cardiac …
contribution of regulated necrosis-like cell death program, such as necroptosis to cardiac …
KLF9 aggravates streptozotocin-induced diabetic cardiomyopathy by inhibiting PPARγ/NRF2 signalling
F Li, J Peng, H Feng, Y Yang, J Gao, C Liu, J Xu… - Cells, 2022 - mdpi.com
Aims: Krüppel-like Factor 9 (KLF9) is a transcription factor that regulates multiple disease
processes. Studies have focused on the role of KLF9 in the redox system. In this study, we …
processes. Studies have focused on the role of KLF9 in the redox system. In this study, we …
[Retracted] Knockdown of miR‐372‐3p Inhibits the Development of Diabetic Cardiomyopathy by Accelerating Angiogenesis via Activating the PI3K/AKT/mTOR/HIF‐1α …
Z Han, D Zhao, M Han, R Zhang… - Oxidative Medicine and …, 2022 - Wiley Online Library
Background. DCM is the most common and malignant complication of diabetes. It is
characterized by myocardial dilatation, hypertrophy, fibrosis, ventricular remodeling, and …
characterized by myocardial dilatation, hypertrophy, fibrosis, ventricular remodeling, and …
Proteomic analysis suggests altered mitochondrial metabolic profile associated with diabetic cardiomyopathy
Diabetic cardiomyopathy (DbCM) occurs independently of cardiovascular diseases or
hypertension, leading to heart failure and increased risk for death in diabetic patients. To …
hypertension, leading to heart failure and increased risk for death in diabetic patients. To …
[HTML][HTML] Mechanisms for the development of heart failure and improvement of cardiac function by angiotensin-converting enzyme inhibitors
SK Bhullar, AK Shah, NS Dhalla - Scripta Medica, 2022 - scindeks.ceon.rs
Angiotensin-converting enzyme (ACE) inhibitors, which prevent the conversion of
angiotensin I to angiotensin II, are well-known for the treatments of cardiovascular diseases …
angiotensin I to angiotensin II, are well-known for the treatments of cardiovascular diseases …