Naringenin: A potential flavonoid phytochemical for cancer therapy

M Motallebi, M Bhia, HF Rajani, I Bhia, H Tabarraei… - Life Sciences, 2022 - Elsevier
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

Stinging Nettle (Urtica dioica L.): Nutritional Composition, Bioactive Compounds, and Food Functional Properties

HP Devkota, KR Paudel, S Khanal, A Baral, N Panth… - Molecules, 2022 - mdpi.com
Stinging nettle (Urtica dioica L., Urticaceae) is commonly found in Asia, Africa, and Europe
and has a long history of being used as food and traditional medicine. Recently, this plant is …

Attenuation of cigarette-smoke-induced oxidative stress, senescence, and inflammation by berberine-loaded liquid crystalline nanoparticles: in vitro study in 16HBE …

KR Paudel, N Panth, B Manandhar, SK Singh, G Gupta… - Antioxidants, 2022 - mdpi.com
Cigarette smoke is considered a primary risk factor for chronic obstructive pulmonary
disease. Numerous toxicants present in cigarette smoke are known to induce oxidative …

Berberine-loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

KR Paudel, M Mehta, GHS Yin, LL Yen… - … Science and Pollution …, 2022 - Springer
Non-small cell lung cancer (NSCLC) is reported to have a high incidence rate and is one of
the most prevalent types of cancer contributing towards 85% of all incidences of lung cancer …

Inhalation delivery of repurposed drugs for lung cancer: approaches, benefits and challenges

P Kumbhar, A Manjappa, R Shah, NK Jha… - Journal of Controlled …, 2022 - Elsevier
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …

Targeting the mitochondria in chronic respiratory diseases

DK Chellappan, KR Paudel, NW Tan, KS Cheong… - Mitochondrion, 2022 - Elsevier
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also
the source of respiratory ATP. Recently published studies have demonstrated that …

An overview of epithelial growth factor receptor (EGFR) inhibitors in cancer therapy

KS Alharbi, MAJ Shaikh, O Afzal, ASA Altamimi… - Chemico-Biological …, 2022 - Elsevier
Epithelial growth factor receptor (EGFR), a transmembrane receptor on the cell surface,
carries extracellular messages into the cell and alters the activity of the nucleus through …

Unravelling the therapeutic potential of nano-delivered functional foods in chronic respiratory diseases

DD Clarence, KR Paudel, B Manandhar, SK Singh… - Nutrients, 2022 - mdpi.com
Chronic inflammation of the respiratory tract is one of the most concerning public health
issues, as it can lead to chronic respiratory diseases (CRDs), some of which are more …

Citrus maxima (Brum.) Merr. (Rutaceae): Bioactive Chemical Constituents and Pharmacological Activities

B Sapkota, HP Devkota… - … Based Complementary and …, 2022 - Wiley Online Library
Citrus maxima (Burm). Merr.(family Rutaceae), commonly known as Pomelo, is an
ethnomedicinally, pharmacologically, and phytochemically valued species. Various …

Evaluation of the Cytotoxic Activity and Anti-Migratory Effect of Berberine–Phytantriol Liquid Crystalline Nanoparticle Formulation on Non-Small-Cell Lung Cancer In …

AM Alnuqaydan, AG Almutary, M Azam, B Manandhar… - Pharmaceutics, 2022 - mdpi.com
Non-small-cell lung cancer (NSCLC) is the most common form of lung cancer, which is a
leading cause of cancer-related deaths worldwide. Berberine is an isoquinoline alkaloid that …